Musculoskeletal system disorders
Developmental and genetic diseases
1. Achondroplasia
-Defect of bone formation resulting in dwarfism
-defective formation of long bones which do not lengthen.
-normal trunk, short limbs, relatively large heads.
2. Osteogenesis imperfecta
- Group of inherited diseases resulting from defective collagen
type I
- Results in production of osteopenic bone which is weak.
Infection & circulatory disturbances
Osteomyelitis
- Inflammation of bones, most commonly due to bacterial
infection.
Aseptic necrosis (avascular necrosis,
osteonecrosis)
- Death of part of a bone secondary to infarct
- Infarct occurs as a consequence of ischemia.
Joint disease
Osteoarthritis
- Chronic degenerative disease of articular joints with loss
of cartilage.
Developmental and genetic diseases
1. Achondroplasia
-Defect of bone formation resulting in dwarfism
-defective formation of long bones which do not lengthen.
-normal trunk, short limbs, relatively large heads.
2. Osteogenesis imperfecta
- Group of inherited diseases resulting from defective collagen
type I
- Results in production of osteopenic bone which is weak.
Infection & circulatory disturbances
Osteomyelitis
- Inflammation of bones, most commonly due to bacterial
infection.
Aseptic necrosis (avascular necrosis,
osteonecrosis)
- Death of part of a bone secondary to infarct
- Infarct occurs as a consequence of ischemia.
Joint disease
Osteoarthritis
- Chronic degenerative disease of articular joints with loss
of cartilage.
