MSN 611 PHARM FINAL exam wit verified solutions available and graded A+

Where are H4 receptors located? - ANSeosinophils, neutrophils, and T cells In the stomach, histamine is released by - ANSenterochromaffin-like cells Toxic effect of first generation antihistamines - ANSconvulsions, postural hypotension (falls), and cardiac arrhythmias s/s hallucinations, incoordination, convulsions, arrhythmias and fever anaphylaxis and antihistamines - ANSantihistamines alone are not sufficient treatment. Patients should receive epi. Can be added on as adjuvant treatment central nervous system side effects of antihistamines in elderly - ANScoordination problems, fatigue, temporary cognitive impairment not postural hypotension-- this is toxicity indication of H2 antihistamines - ANSinhibit the secretion of gastric acid intranasal should be used only after intranasal glucocorticoids second generation antihistamine that cannot be removed by HD - ANScetirizine hydrochloride all day allergy zyrtec initial selection of antimicrobial therapy - ANStypically empiric food-drug or drug-drug interactions with antibacterial medications are usually addressed by - ANSseparating the administration times of avoiding the combination multiple drug combination treatment for TB - ANStypically 3-6 months active- initial 2 months daily tx isoniazid, rifampin, pyrazinamide and ethambutol. cont 4-7 months combo of isoniaid & rifampin for total of 6-9 months latent- isoniazid qd 6-9 months. rifampin qd 4 months. isoniazid & rifapentine weekly 3 months description of IFN-B - ANSFN-B have antiviral properties but used in MS IFN-y1b injection for preventing infection in pts with granulomatous disease combined with antibacterals and antifungals IFN-y rarely used for salvage tx myobacterial infections