NUR 2474 Pharm Module With a grade of A+ and verified solutions available

S/S of Alzheimers Disease? - ANSmemory loss, confusion, feeling disoriented, impaired judgement, inability to self care, cannot do ADLs What is happening in the brain before one begins medication with Alzheimers? - ANSthere is reduced Ach or cholinergic transmission with levels below 90%, the neurons are degenerated. Main medication given for Alzheimers disease? - ANSdonepezil What is the prognosis with Alzheimers? - ANSit is irreversible and incurable, but medication use can slow its progression What does donepezil do? - ANSprevent Ach breakdown at the neural level, therefor increasing concentration of the neurotransmitter available for reuptake. SE of donepezil? - ANSHA, dizziness, GI effects- N,V, bronchoconstriction What is one thing we need to teach the patient and family about use of the medication donepezil? - ANSremember to take the medication on time and to follow correct dose. often times patient who take this drug may forget to take it or that they have already taken it, so having a supportive person will help with management. S/S of Parkinson's - ANSdyskinesia, tremors, rigidity, postural instability, bradykinesia, mask like face, shifting gait, pill rolling movements, autonomic disturbance, depression and psychosis. What is happening in the brain before one begins medication with Parkinsons? - ANSThere is a low amount of dopamine, and increase Ach stimulation of GABA Main medications for Parkinsons - ANSLevodopa/Carbidopa selegiline Lasting effects of levodopa/carbidopa over time - ANSlasts 2-5 years then will wear off over time Why is levodopa used with carbidopa? - ANSenhances the effects of levodopa and helps reduce N and V associated.