, MANUAL OF
ENDOCRINOLOGY AND
METABOLISM
Fifth Edition
p. i
, MANUAL OF
ENDOCRINOLOGY AND
METABOLISM
Fifth Edition
Editor
Norman Lavin, MD, PhD, FAAP, FACE
Clinical Professor of Endocrinology and Pediatrics
Director of Clinical Education in Endocrinology
UCLA School of Medicine
Los Angeles, California
Director of Medical Education
Providence Tarzana Regional Medical Center
Tarzana, California
Editor-in-Chief: “Growth, Growth Hormone, IGF-1, and Metabolism” London, England
p. iii
, Acquisitions Editor: Kate Heaney
Development Editor: Kristina Oberle
Editorial Coordinator: David Murphy, Jr
Marketing Manager: Rachel Mante Leung
Production Project Manager: Barton Dudlick
Design Coordinator: Holly McLaughlin
Manufacturing Coordinator: Beth Welsh
Prepress Vendor: S4Carlisle Publishing Services
Fifth Edition
Copyright © 2019 by Wolters Kluwer.
All rights reserved. This book is protected by copyright. No part of this book may be reproduced or
transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies,
or utilized by any information storage and retrieval system without written permission from the copyright
owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this
book prepared by individuals as part of their official duties as U.S. government employees are not covered
by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two
Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at , or via
our website at lww.com (products and services).
9 8 7 6 5 4 3 2 1
Printed in China
Library of Congress Cataloging-in-Publication Data
Names: Lavin, Norman, editor.
Title: Manual of endocrinology and metabolism / [edited by] Norman Lavin,
M.D., Ph.D., F.A.A.P., F.A.C.E., Clinical Professor of Endocrinology and
Pediatrics, Director of Clinical Education in Endocrinology, UCLA School
of Medicine, Los Angeles, California; editor-in-chief: Growth, Growth
Hormone, IGF-1, and Metabolism, London, England; director of the Diabetes
Care Center and Director of Medical Education, Providence Tarzana Regional
Medical Center, Tarzana, California.
Description: Fifth edition. | Philadelphia: Wolters Kluwer Health, [2019] |
Includes bibliographical references and index.
Identifiers: LCCN 2018000484 | eISBN 9781975107314
Subjects: LCSH: Endocrinology—Handbooks, manuals, etc. | Endocrine
glands—Diseases—Handbooks, manuals, etc. |
Metabolism—Disorders—Handbooks, manuals, etc.
Classification: LCC RC648 | M365 2019 | DDC 616.4—dc23
LC record available at https://lccn.loc.gov/2018000484
This work is provided “as is,” and the publisher disclaims any and all warranties, express or implied,
including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.
This work is no substitute for individual patient assessment based upon healthcare professionals’
examination of each patient and consideration of, among other things, age, weight, gender, current or prior
medical conditions, medication history, laboratory data and other factors unique to the patient. The
publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare
professionals, and not the publisher, are solely responsible for the use of this work including all medical
judgments and for any resulting diagnosis and treatments.
ENDOCRINOLOGY AND
METABOLISM
Fifth Edition
p. i
, MANUAL OF
ENDOCRINOLOGY AND
METABOLISM
Fifth Edition
Editor
Norman Lavin, MD, PhD, FAAP, FACE
Clinical Professor of Endocrinology and Pediatrics
Director of Clinical Education in Endocrinology
UCLA School of Medicine
Los Angeles, California
Director of Medical Education
Providence Tarzana Regional Medical Center
Tarzana, California
Editor-in-Chief: “Growth, Growth Hormone, IGF-1, and Metabolism” London, England
p. iii
, Acquisitions Editor: Kate Heaney
Development Editor: Kristina Oberle
Editorial Coordinator: David Murphy, Jr
Marketing Manager: Rachel Mante Leung
Production Project Manager: Barton Dudlick
Design Coordinator: Holly McLaughlin
Manufacturing Coordinator: Beth Welsh
Prepress Vendor: S4Carlisle Publishing Services
Fifth Edition
Copyright © 2019 by Wolters Kluwer.
All rights reserved. This book is protected by copyright. No part of this book may be reproduced or
transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies,
or utilized by any information storage and retrieval system without written permission from the copyright
owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this
book prepared by individuals as part of their official duties as U.S. government employees are not covered
by the above-mentioned copyright. To request permission, please contact Wolters Kluwer at Two
Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at , or via
our website at lww.com (products and services).
9 8 7 6 5 4 3 2 1
Printed in China
Library of Congress Cataloging-in-Publication Data
Names: Lavin, Norman, editor.
Title: Manual of endocrinology and metabolism / [edited by] Norman Lavin,
M.D., Ph.D., F.A.A.P., F.A.C.E., Clinical Professor of Endocrinology and
Pediatrics, Director of Clinical Education in Endocrinology, UCLA School
of Medicine, Los Angeles, California; editor-in-chief: Growth, Growth
Hormone, IGF-1, and Metabolism, London, England; director of the Diabetes
Care Center and Director of Medical Education, Providence Tarzana Regional
Medical Center, Tarzana, California.
Description: Fifth edition. | Philadelphia: Wolters Kluwer Health, [2019] |
Includes bibliographical references and index.
Identifiers: LCCN 2018000484 | eISBN 9781975107314
Subjects: LCSH: Endocrinology—Handbooks, manuals, etc. | Endocrine
glands—Diseases—Handbooks, manuals, etc. |
Metabolism—Disorders—Handbooks, manuals, etc.
Classification: LCC RC648 | M365 2019 | DDC 616.4—dc23
LC record available at https://lccn.loc.gov/2018000484
This work is provided “as is,” and the publisher disclaims any and all warranties, express or implied,
including any warranties as to accuracy, comprehensiveness, or currency of the content of this work.
This work is no substitute for individual patient assessment based upon healthcare professionals’
examination of each patient and consideration of, among other things, age, weight, gender, current or prior
medical conditions, medication history, laboratory data and other factors unique to the patient. The
publisher does not provide medical advice or guidance and this work is merely a reference tool. Healthcare
professionals, and not the publisher, are solely responsible for the use of this work including all medical
judgments and for any resulting diagnosis and treatments.
