(Review)/Latest Update/NEW!!!!
INFECTIOUS ENDOCARDITIS – yellow tab 10, p 1173
• Infection and inflammation of the endocardium, especially the cardiac valves
• Bacterial – strep, staph, enterococci
• 3 elements – endocardial damage, blood-bourne pathogen adherence to the
damaged endocardial surface, formation of infective endocardial vegetations
• MANIFESTATIONS
o Acute, subacure, or chronic
o Causes varying degrees of valvular dysfunction
o Can have manifestations involving several organs
o Classic symptoms: fever, new or changed cardiac murmur, petechial
lesions of the skin, conjunctivae, or oral mucosa
▪ Oslers nodes, janeway lesions
• EVALUATION/TREATMENT
o Evaluate for emboli
o Antimicrobial therapy
VALVULAR FUNCTION – yellow tab 11, p 1086
• One-way blood flow through the heart, maintain pressure gradients
• TRICUSPID VALVE
o Right AV valve
o Has 3 cusps
• MITRAL VALVE
o Left AV valve
o Cone-shaped funnel that extends into cusps
OXYGENATED BLOOD FLOW – yellow tab 12, p 1088
• Superior and inferior vena cava and the coronary sinus
• Rt. atrium
• Tricuspid valve (also called the rt. atrioventricular valve)
• Rt. ventricle
• Pulmonary semilunar valve
• Pulmonary trunk
,
, •
• Right and left pulmonary arteries (only time there is deoxygenated
blood in artery)
• Lungs
• Pulmonary veins (only time there is oxygenated blood in vein)
• Lt. atrium
• Bicuspid valve (also called the lt. atrioventricular valve or mitral
valve)
• Lt. ventricle
• Aortic semilunar valve