(Verified Answers)
Know the route of administration for newer agent asenapine (Saphris) and what
instructions should be given to the patient regarding administration.
Sublingual
Know and describe the top atypical antipsychotic with greatest incidence of prolonged
QTc interval.
Ziprasidone (Geodon).
Know which antipsychotics have specific instructions for minimum food intake or diet
restrictions.
Lurasidone (Latuda)
Know an alternative atypical antipsychotic for a patient who has developed diabetes and
has a significant weight gain from treatment with olanzapine.
Aripiprazole (Abilify)
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this week's
granulocyte count is less than 500mm3. What is the most appropriate recommendation
for drug therapy?
Discontinue and do not re-start
Know the common effects of smoking along with antipsychotic drug therapy such as
olanzapine.
Decreases the plasma levels of Olanzapine (Zyprexa) because of its metabolism at
CYP450 enzyme.
Know what a painful muscle spasm with neck muscles pulling a patient's head to the
side called and Name a common drug therapy to relieve this symptom.
Dystonia
Know the role of buspirone in the treatment of anxiety and the recommended dose and
time for onset of action.
Takes 3 to 4 weeks for full effect
Know what medication may be an option for patients noncompliant on antipsychotics
resulting in multiple hospital stays.
Risperdal Consta (risperidone)
Know baseline labs and vital measurements tests for the patient who will be prescribed
an antipsychotic such as quetiapine (Seroquel).
Lipid, Fasting Blood Sugar, Family History *NOT CPK*
Describe common side effects/disadvantages of antihistamines.
anticholinergic effects
Identify 3-4 disorders/situations when benzodiazepines may be indicated.
Alcohol withdrawal, Benzodiazepine withdrawal, Acute Agitation, Panic Attack, Sleep
Disorder, Seizures
Describe 2-3 common side effects of atypical antipsychotics.
Weight gain, Sedation, Metabolic Syndrome
Know and describe the name of long-acting olanzapine and a key adverse side effect.
Zyprexa Relprevv *Post injection delirium syndrome*