Nurs 6501 Advanced Pathophysiology Test questions with accurate solutions available and graded A+

nonspecific immunity (4) - ANSsecretory activity of phagocytes barriers: i.e. skin, GI mucus, respiratory cilia chemicals: lysozyme, gastric acid flushing: tears, sweat, urine, GI motility specific immunity - ANSlymphocytes, antibodies effects seen with cytokine release (3) - ANSdilate intact arterioles and capillaries (hypermeia [congestion], redness [rubor] and heat [calor]) increase capillary permeability (swelling [tumor], WBCs and clot factors can become involved) stimulate free nerve endings (pain) seen by the major histocompatibility complex (MHC); confirms that a nucleated cell is "self" - ANSMHCI mononuclear phagocyte system is located strategically throughout (5) - ANSmicroglia avleolar macrophages kupffer cells kidney mesangial cells lymph nodes primary lymphoid organs (2) - ANSbone marrow, thymus secondary lyphoid organs (4) - ANStonsils spleen lymph nodes and lymphatics peyer patches type of granulocyte that act as early responders; they are phagocytotic but also secrete enzymes; increase seen in acute infection - ANSneutrophils type of granulocyte seen in an allergic response; lots of histamine release; bind IgE to surface receptors - ANSbasophils type of granulocyte seen in response to parasite; release inflammatory mediators; bind IgE on parasites - ANSeosinophils large, powerful phagocyte; long-lived and mobile - ANSmacrophages