, INTRODUCTION
• The two broad categories of coronary heart disea
chronic coronary artery disease (CAD) and acute
coronary syndromes
• Stable angina is the classic initial manifestation
chronic CAD.
• Acute coronary syndromes, an umbrella term used
describe the sequelae of unstable angina and myo
infarction (MI) with or without elevation in the ST
segment.
,
, OVERVIEW OF CORONARY ARTERY DISEASE
• CAD is the result of damage to the intima , or inner layer, of the
arteries, leading to a buildup of lipids and fibrous matter.
• In CAD, increased blood levels of low-density lipoprotein
(LDL) irritate and damage the intima of the coronary artery
• The development of fixed atherosclerotic plaque narrows the
lumen of the artery, which restricts the flow of oxygen-carryi
blood.
• When oxygen supply is insufficient, especially during periods o
high oxygen demand (e.g., with physical exertion), cardiac
ischemia occurs and the patient may experience stable angina.
• The two broad categories of coronary heart disea
chronic coronary artery disease (CAD) and acute
coronary syndromes
• Stable angina is the classic initial manifestation
chronic CAD.
• Acute coronary syndromes, an umbrella term used
describe the sequelae of unstable angina and myo
infarction (MI) with or without elevation in the ST
segment.
,
, OVERVIEW OF CORONARY ARTERY DISEASE
• CAD is the result of damage to the intima , or inner layer, of the
arteries, leading to a buildup of lipids and fibrous matter.
• In CAD, increased blood levels of low-density lipoprotein
(LDL) irritate and damage the intima of the coronary artery
• The development of fixed atherosclerotic plaque narrows the
lumen of the artery, which restricts the flow of oxygen-carryi
blood.
• When oxygen supply is insufficient, especially during periods o
high oxygen demand (e.g., with physical exertion), cardiac
ischemia occurs and the patient may experience stable angina.
