ASCP MLS Practice exam 2023/160
Questions and Answers
What feature is most often found with patients with a
splenectomy on a Wright's stained blood smear? - -Howell-Jolly
bodies
-Patients with antibody to the following antigen are immune to
Hepatitis B: - -Surface antigen (HbSAg)
-Which two of the following tests are helpful for documenting
previous Streptococcal throat and skin infections: - -ASO titer
and Anti-DNase B
-In mass spectrometry, the "appearance potential" is defined as
the: - -Minimum energy required for the appearance of a
particular fragment ion in mass spectrum
-What is generally accepted as the lower threshold value for
semen pH from fertile males? - -7.2
-Coulometry: - -An automated method for measuring chloride
which generates silver ions in the reaction
-Erythroleukemia: - -Also known as Acute Myelogenous
Leukemia type M6. This type is associated with either the
presence of both erythroid and myeloid precursors OR strictly
erythroid precursors.
-Myelomonocytic leukemia - -Is associated with an increase in
myeloid and monocytic cell precursors, but not red blood cell
precursors
-Species that are Lysine (+), arginine (=) and ornithine (+): - -
Enterobacter aerogenes, Edwardsiella species and most Serratia
species
-Lysine reaction for all Citrobacter: - -Negative
, -Key identifying characteristic for Pantoa (Enterobacter)
agglomerans: - -negative reactions for the three decarboxylases
commonly tested ( Lysine, arginine and ornithine)
-Which organism is MOST likely responsible for septic reactions
associated with Red Blood Cell transfusions? - -Yersina
entercolitica is most likely responsible for septic reactions in
transfusions of Red Blood Cells. This organism is usually
acquired by ingestion of contaminated food and causes mild
symptoms of abdominal pain and diarrhea. Growth of Y.
entercolitica is enhanced in iron-rich environments such as red
cell components.
-Gaucher's disease - -The most common lysosomal storage
disease caused by insufficient activity of the lysosomal enzyme
glucocerebrosidase that leads to the deposition of
glucocerebroside in cells of the macrophage-monocyte system.
-Diseases associated with dysfunctions of polymorphonuclear
neutrophils (PMNs) - -Chediak-Higashi syndrome (CH), Chronic
granulomatous disease (CGD), Myeloperoxidase deficiency
(MPO)
-Nephrotic Syndrome: - -Caused by damage to the kidneys,
especially the basement membrane of the glomerulus; which
causes abnormal excretion of protein and red blood cells in the
urine. Fats are also present in the urine in most cases. A foamy
appearance of the urine is a key characteristic of this condition.
Clinical symptoms include:
Swelling
Weight gain from fluid retention
Poor appetite
High blood pressure
-Key Biochemical reactions for Enterobacteriaceae: - -The key
biochemical reactions by which the family Enterobacteriaceae
can be identified include fermentation of carbohydrates,
, reduction of nitrates to nitrites and the absence of cytochrome
oxidase activity.
-ANA - -See 2 quiz #27
-Prozone effect: - -Results in a false positive reaction; is the
result of antibody excess and dilution of antibody can help
prevent its occurrence
-Purpose of a bi-chromatic analyzer with dual wavelengths is: - -
Minimize the effect of interference
-Key characteristics of Micrococcus: - -Susceptible to bacitracin
("A") and resistant to furazolidone; gram positive cocci in tetras,
bacteria cells of micrococcus luteus are larger than those of the
staphylococci and can arrange in tetras
-What is the glomerular filtration rate for a patient with a serum
creatinine of 2 mg/dL, if the urine creatinine was 124 mg/dL and
the urine volume was 2.2 L/24 hrs? - -95 mL/min
One method of calculating a glomerular filtration rate is using
creatinine and urine volume to determine creatinine clearance.
The equation is as follows:
Creatinine Clearance = (urine creatinine X urine flow rate) /
plasma creatinine; where urine flow rate = volume in mL /24
hours x h/60 min)
In this case = creatinine clearance = 124 X (2200/24 x hour/60) /
2 = 94.7 or 95 ml/min
-Estrogen and progesterone markers are most commonly used to
provide prognostic information about: - -Breast cancer
-The prozone effect ( when performing a screening titer) is most
likely to result in: - -Prozone effect (due to antibody excess) will
result in an initial false negative in spite of the large amount of
antibody in the serum, followed by a positive result as the
specimen is diluted.
Questions and Answers
What feature is most often found with patients with a
splenectomy on a Wright's stained blood smear? - -Howell-Jolly
bodies
-Patients with antibody to the following antigen are immune to
Hepatitis B: - -Surface antigen (HbSAg)
-Which two of the following tests are helpful for documenting
previous Streptococcal throat and skin infections: - -ASO titer
and Anti-DNase B
-In mass spectrometry, the "appearance potential" is defined as
the: - -Minimum energy required for the appearance of a
particular fragment ion in mass spectrum
-What is generally accepted as the lower threshold value for
semen pH from fertile males? - -7.2
-Coulometry: - -An automated method for measuring chloride
which generates silver ions in the reaction
-Erythroleukemia: - -Also known as Acute Myelogenous
Leukemia type M6. This type is associated with either the
presence of both erythroid and myeloid precursors OR strictly
erythroid precursors.
-Myelomonocytic leukemia - -Is associated with an increase in
myeloid and monocytic cell precursors, but not red blood cell
precursors
-Species that are Lysine (+), arginine (=) and ornithine (+): - -
Enterobacter aerogenes, Edwardsiella species and most Serratia
species
-Lysine reaction for all Citrobacter: - -Negative
, -Key identifying characteristic for Pantoa (Enterobacter)
agglomerans: - -negative reactions for the three decarboxylases
commonly tested ( Lysine, arginine and ornithine)
-Which organism is MOST likely responsible for septic reactions
associated with Red Blood Cell transfusions? - -Yersina
entercolitica is most likely responsible for septic reactions in
transfusions of Red Blood Cells. This organism is usually
acquired by ingestion of contaminated food and causes mild
symptoms of abdominal pain and diarrhea. Growth of Y.
entercolitica is enhanced in iron-rich environments such as red
cell components.
-Gaucher's disease - -The most common lysosomal storage
disease caused by insufficient activity of the lysosomal enzyme
glucocerebrosidase that leads to the deposition of
glucocerebroside in cells of the macrophage-monocyte system.
-Diseases associated with dysfunctions of polymorphonuclear
neutrophils (PMNs) - -Chediak-Higashi syndrome (CH), Chronic
granulomatous disease (CGD), Myeloperoxidase deficiency
(MPO)
-Nephrotic Syndrome: - -Caused by damage to the kidneys,
especially the basement membrane of the glomerulus; which
causes abnormal excretion of protein and red blood cells in the
urine. Fats are also present in the urine in most cases. A foamy
appearance of the urine is a key characteristic of this condition.
Clinical symptoms include:
Swelling
Weight gain from fluid retention
Poor appetite
High blood pressure
-Key Biochemical reactions for Enterobacteriaceae: - -The key
biochemical reactions by which the family Enterobacteriaceae
can be identified include fermentation of carbohydrates,
, reduction of nitrates to nitrites and the absence of cytochrome
oxidase activity.
-ANA - -See 2 quiz #27
-Prozone effect: - -Results in a false positive reaction; is the
result of antibody excess and dilution of antibody can help
prevent its occurrence
-Purpose of a bi-chromatic analyzer with dual wavelengths is: - -
Minimize the effect of interference
-Key characteristics of Micrococcus: - -Susceptible to bacitracin
("A") and resistant to furazolidone; gram positive cocci in tetras,
bacteria cells of micrococcus luteus are larger than those of the
staphylococci and can arrange in tetras
-What is the glomerular filtration rate for a patient with a serum
creatinine of 2 mg/dL, if the urine creatinine was 124 mg/dL and
the urine volume was 2.2 L/24 hrs? - -95 mL/min
One method of calculating a glomerular filtration rate is using
creatinine and urine volume to determine creatinine clearance.
The equation is as follows:
Creatinine Clearance = (urine creatinine X urine flow rate) /
plasma creatinine; where urine flow rate = volume in mL /24
hours x h/60 min)
In this case = creatinine clearance = 124 X (2200/24 x hour/60) /
2 = 94.7 or 95 ml/min
-Estrogen and progesterone markers are most commonly used to
provide prognostic information about: - -Breast cancer
-The prozone effect ( when performing a screening titer) is most
likely to result in: - -Prozone effect (due to antibody excess) will
result in an initial false negative in spite of the large amount of
antibody in the serum, followed by a positive result as the
specimen is diluted.
