REPLICATION OF
VIRUS
Dr. Moto
,Virus (Latin, poison)
Viruses are sub-cellular, non-living, infectious
entities which only become part of a living system
when they have infected host cells, a form of
borrowed life (van Regenmortel, 2000)
Viruses are obligate intracellular parasites.
They need the help of a host cell for
their replication.
All viruses have to penetrate, replicate & come out
of a cell.
Infection of a cell by virus may result in various
types of infection.
,
, Stages of virus replication
Phase– I Initiation: This stage is characterized by
introduction of genetic material of the virus into the cell.
• Attachment
• Penetration
• Uncoating
Phase – II Replication: This stage is characterized by the
genome size, composition and organization of viruses. There
is no single pattern of replication. But all make proteins with 3
sets of functions to:
•Ensure replication of the genome
•Package the genome into virus particles
•Alter the metabolism of the infected cell so that viruses are
produced.
VIRUS
Dr. Moto
,Virus (Latin, poison)
Viruses are sub-cellular, non-living, infectious
entities which only become part of a living system
when they have infected host cells, a form of
borrowed life (van Regenmortel, 2000)
Viruses are obligate intracellular parasites.
They need the help of a host cell for
their replication.
All viruses have to penetrate, replicate & come out
of a cell.
Infection of a cell by virus may result in various
types of infection.
,
, Stages of virus replication
Phase– I Initiation: This stage is characterized by
introduction of genetic material of the virus into the cell.
• Attachment
• Penetration
• Uncoating
Phase – II Replication: This stage is characterized by the
genome size, composition and organization of viruses. There
is no single pattern of replication. But all make proteins with 3
sets of functions to:
•Ensure replication of the genome
•Package the genome into virus particles
•Alter the metabolism of the infected cell so that viruses are
produced.
