WGU C785 Biochemistry Final Exam(70 QnS)
2022/2023
Which mRNA sequence results in a polypeptide that contains three amino acids? -Correct Answer-
5' - CUU GAU ACU UAG - 3'
Which RNA sequence would end in the following polypeptide?
Phe-Thr-Val-Stop -Correct Answer- 5' - UUC ACA GUA UAA - 3'
What is the complementary sequence for the following DNA sequence?
5' - GCC ATC TCG AAT - 3' -Correct Answer- 5' - ATT CGA GAT GGC - 3'
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of four
complete PCR cycles? -Correct Answer- 16
What is the function of DNA polymerase in the process of PCR? -Correct Answer- It recognizes the
primers and uses the available dNTPs to replicate the template DNA sequence.
5' - [...] ATT CGC TAG GGC [...] - 3' − Normal DNA
5' - [...] ATT CGC GAG GGC [...] - 3' − Mutant DNA
Which type of mutation and outcome characterizes the Mutant DNA? -Correct Answer- A missense
mutation leading to a longer protein
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
What change in codons corresponds to this mutation? -Correct Answer- GAA to GTA
What are possible blood types of the parents of a patient with blood type AB? -Correct Answer- A
and B
Which pair of chromosomes accurately depicts the genotype of a person with an autosomal
recessive mutant HBB allele and sickle cell anemia? -Correct Answer- option 3- 2 mutant genes on
chromosome 11
Which pair of chromosomes accurately depicts the genotype of a person with an X-linked recessive
mutant ALAS2 allele and sideroblastic anemia? -Correct Answer- option 3, mutated allele
This study source was downloaded by 100000860579690 from CourseHero.com on 04-12-2023 03:34:17 GMT -05:00
https://www.coursehero.com/file/181573584/WGU-C785-Biochemistry-Final-Exampdf/
, Studies have shown that increased expression of two genes called SIRT1 and SIRT2 is associated
with chronic exposure to cocaine and contributes to drug addiction.
What difference in the regions of the SIRT1 and SIRT2 genes in people addicted to cocaine increases
their expression? -Correct Answer- The nucleosomes become more widely spaced.
Mice with low levels of agouti gene expression tend to have yellow fur and are obese, while mice
with higher levels of expression are brown and of normal weight. Studies show that expression of
the agouti gene in mice can be controlled by epigenetics.
Mice with low levels of agouti gene expression tend to have yellow fur and are obese, while mice
with higher levels of expression are brown and of normal weight. Studies show that expression of
the agouti gene in mice can be controlled by epigenetics.
What scenario describes epigenetic regulation of the agouti gene? -Correct Answer- Mother mice
fed methyl-rich diets during pregnancy give birth to offspring with decreased agouti gene
expression compared to those fed a methyl-poor diet.
Oxidative damage to DNA can often result in the alteration of a single nucleotide.
Which DNA repair mechanism would repair this type of damage? -Correct Answer- Base excision
repair
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs when one or more of the
genes that perform nucleotide excision repair are nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the general population? -
Correct Answer- The mutation rate of all other genes is higher due to failure to repair.
Which reaction is responsible for the formation of polypeptides? -Correct Answer- Dehydration
Which portion of the amino acid is inside the box? -Correct Answer- Carboxyl group
Which amino acid side group is polar? -Correct Answer- option 2-one with charge
When placed within a polypeptide chain, which amino acid would interact most favorably with
nonpolar amino acids? -Correct Answer- option 2-non polar
Which term describes the order of amino acids in a peptide chain? -Correct Answer- Primary
structure
When using heat to denature a protein, which force is the first to be disrupted as temperature
increases? -Correct Answer- Hydrophobic interactions
This study source was downloaded by 100000860579690 from CourseHero.com on 04-12-2023 03:34:17 GMT -05:00
https://www.coursehero.com/file/181573584/WGU-C785-Biochemistry-Final-Exampdf/
2022/2023
Which mRNA sequence results in a polypeptide that contains three amino acids? -Correct Answer-
5' - CUU GAU ACU UAG - 3'
Which RNA sequence would end in the following polypeptide?
Phe-Thr-Val-Stop -Correct Answer- 5' - UUC ACA GUA UAA - 3'
What is the complementary sequence for the following DNA sequence?
5' - GCC ATC TCG AAT - 3' -Correct Answer- 5' - ATT CGA GAT GGC - 3'
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of four
complete PCR cycles? -Correct Answer- 16
What is the function of DNA polymerase in the process of PCR? -Correct Answer- It recognizes the
primers and uses the available dNTPs to replicate the template DNA sequence.
5' - [...] ATT CGC TAG GGC [...] - 3' − Normal DNA
5' - [...] ATT CGC GAG GGC [...] - 3' − Mutant DNA
Which type of mutation and outcome characterizes the Mutant DNA? -Correct Answer- A missense
mutation leading to a longer protein
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
What change in codons corresponds to this mutation? -Correct Answer- GAA to GTA
What are possible blood types of the parents of a patient with blood type AB? -Correct Answer- A
and B
Which pair of chromosomes accurately depicts the genotype of a person with an autosomal
recessive mutant HBB allele and sickle cell anemia? -Correct Answer- option 3- 2 mutant genes on
chromosome 11
Which pair of chromosomes accurately depicts the genotype of a person with an X-linked recessive
mutant ALAS2 allele and sideroblastic anemia? -Correct Answer- option 3, mutated allele
This study source was downloaded by 100000860579690 from CourseHero.com on 04-12-2023 03:34:17 GMT -05:00
https://www.coursehero.com/file/181573584/WGU-C785-Biochemistry-Final-Exampdf/
, Studies have shown that increased expression of two genes called SIRT1 and SIRT2 is associated
with chronic exposure to cocaine and contributes to drug addiction.
What difference in the regions of the SIRT1 and SIRT2 genes in people addicted to cocaine increases
their expression? -Correct Answer- The nucleosomes become more widely spaced.
Mice with low levels of agouti gene expression tend to have yellow fur and are obese, while mice
with higher levels of expression are brown and of normal weight. Studies show that expression of
the agouti gene in mice can be controlled by epigenetics.
Mice with low levels of agouti gene expression tend to have yellow fur and are obese, while mice
with higher levels of expression are brown and of normal weight. Studies show that expression of
the agouti gene in mice can be controlled by epigenetics.
What scenario describes epigenetic regulation of the agouti gene? -Correct Answer- Mother mice
fed methyl-rich diets during pregnancy give birth to offspring with decreased agouti gene
expression compared to those fed a methyl-poor diet.
Oxidative damage to DNA can often result in the alteration of a single nucleotide.
Which DNA repair mechanism would repair this type of damage? -Correct Answer- Base excision
repair
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs when one or more of the
genes that perform nucleotide excision repair are nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the general population? -
Correct Answer- The mutation rate of all other genes is higher due to failure to repair.
Which reaction is responsible for the formation of polypeptides? -Correct Answer- Dehydration
Which portion of the amino acid is inside the box? -Correct Answer- Carboxyl group
Which amino acid side group is polar? -Correct Answer- option 2-one with charge
When placed within a polypeptide chain, which amino acid would interact most favorably with
nonpolar amino acids? -Correct Answer- option 2-non polar
Which term describes the order of amino acids in a peptide chain? -Correct Answer- Primary
structure
When using heat to denature a protein, which force is the first to be disrupted as temperature
increases? -Correct Answer- Hydrophobic interactions
This study source was downloaded by 100000860579690 from CourseHero.com on 04-12-2023 03:34:17 GMT -05:00
https://www.coursehero.com/file/181573584/WGU-C785-Biochemistry-Final-Exampdf/
