Department of Cognitive Neuroscience – Behavioural Neurogenetics
UMC St. Radboud, Nijmegen, The Netherlands
Dr. Judith Homberg
Serotonin
,R.E.B, 4MedStudents.com, 2003
Neurotransmitters
Properties of neurotransmitters:
1) synthesized in the presynaptic neuron
2) Localized to vesicles in the presynaptic neuron
3) Released from the presynaptic neuron under
physiological conditions
4) Rapidly removed from the synaptic cleft by uptake or
degradation
5) Presence of receptor on the post-synaptic neuron
6) Binding to the receptor elicits a biological response
2
,
, Neurotransmitters found in the nervous system
Glutamate (excitatory)
GABA (inhibitory)
Glycine (inhibitory)
Acetylcholine
Aspartate
Dopamine
Histamine
Norepinephrine
Serotonin
UMC St. Radboud, Nijmegen, The Netherlands
Dr. Judith Homberg
Serotonin
,R.E.B, 4MedStudents.com, 2003
Neurotransmitters
Properties of neurotransmitters:
1) synthesized in the presynaptic neuron
2) Localized to vesicles in the presynaptic neuron
3) Released from the presynaptic neuron under
physiological conditions
4) Rapidly removed from the synaptic cleft by uptake or
degradation
5) Presence of receptor on the post-synaptic neuron
6) Binding to the receptor elicits a biological response
2
,
, Neurotransmitters found in the nervous system
Glutamate (excitatory)
GABA (inhibitory)
Glycine (inhibitory)
Acetylcholine
Aspartate
Dopamine
Histamine
Norepinephrine
Serotonin
