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Summary BMS 2042 assignment

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it is for the nematode group

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BMS2042 LEC 5 NOTE

1. Forward
2. Reverse genetics - change genotypes and transcriptome= look at functional
consequences
Phenotype cusses when gene on unknown function is manipulated


Figuring out gene function

Related

Conservation of genes proteins


High conserved, same function in yeast eg and in humans


Use model organised to determine then translate those finding in human system with. A
degree of confidence

LONGER BRANCH = MORE DISTANTLY RELATED


ORTHALOGUES
Homologues Genes/proteins found in different species
PARALOGOUS
Homologues genes Genes/proteins found in same species
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