BIO 3200 EXAM 3 November 15, 2016 WSU ID#:

Directions: On your answer sheet, fill in your 1) NAME and 2) WSU ID#. Use a #2 pencil and erase thoroughly if needed. Keep your answer sheet covered with your exam except when entering an answer. 1. In the spleen, hemoglobin is metabolized to a) myoglobin b) bilirubin c) transferrin d) fetal hemoglobin e) erythropoietin 2. Platelets are produced from a) reticulocytes b) macrophages c) granular cells d) macula densa cells e) megakaryocytes 3. Many steps in the coagulation cascade require a) Ca2+ b) Mg2+ c) HCO3- d) Cl- e) Fe3+ 4. Which of the following is not a protease or peptidase? a) thrombin b) plasmin c) renin d) angiotensin converting enzyme e) ferritin 5. Serotonin and thromboxane A2 are released by a) erythrocytes b) platelets c) macrophages d) granular cells e) goblet cells 6. Lack of factor VIII or factor IX causes a) sickle cell anemia b) jaundice c) hemophilia d) atherosclerosis e) hypertension 7. Exposed collagen initiates a) the intrinsic pathway of the coagulation cascade b) the extrinsic pathway of the coagulation cascade c) platelet plug formation d) production of hypoxia-inducible factor 1 e) both a and c 8. Tissue plasminogen activator activates the protein that a) dissolves fibrin polymers b) forms fibrin polymers c) converts angiotensin I to angiotensin II d) transports iron in plasma e) causes platelet aggregation 9. If pO2 in alveoli is low a) local arterioles will constrict b) local arterioles will dilate c) local bronchioles will constrict d) the hypothalamus will release vasopressin e) both a and c 10. Ventilation rate x (tidal volume – dead space) is equal to a) expiratory reserve volume b) total pulmonary ventilation c) clearance d) alveolar ventilation e) intrapleural pressure 11. During inspiration a) the alveolar pressure rises then falls b) air moves out of the lungs c) the intrapleural pressure drops d) the intrapleural pressure rises e) both a and d 12. Particulates are moved up and out of the airways by a) Surfactant b) Pleural fluid c) Arterioles d) Bile e) Mucus 13. Surface tension changes associated with expansion and contraction of the lungs are reduced by a) elastic fibers around the alveoli b) surfactant produced by type II alveolar cells c) dilation of bronchioles d) dilation of pulmonary arterioles e) incompressibility of pleural fluid 14. The volume of air moved in or out in a single normal breath is called the a) expiratory reserve b) inspiratory capacity c) tidal volume d) residual volume e) functional residual capacity 15. Gas exchange in the lungs occurs across a) type I alveolar cells b) columnar epithelial cells c) capillary endothelial cells d) goblet cells e) both a and c 16. The airway epithelium is “leaky” because a) Proteins can leak through the epithelium b) Na+ and H2O can pass through the paracellular pathway c) Surfactant makes the epithelium more permeable to salts d) Na+ and H2O can move through the transcellular pathway e) The NKCC transporter allows Na+, K+, and 2 Cl- to enter the epithelial cells