Final Exam - Pharmacology ECPI 2023 Study Guide

Nicotinic N (neuronal) Location - Correct Answer All autonomic nervous system ganglia and the adrenal medulla Nicotinic N (neuronal) response - Correct Answer Stimulation of parasympathetic and sympathetic post-ganglionic nerves and release of epinephrine from adrenal medulla Nicotinic M (muscle) Location - Correct Answer Neuromuscular junction Nicotinic M (muscle) Response - Correct Answer contraction of skeletal muscle Muscarinic Locations - Correct Answer Eye, Heart, Lung, Bladder, GI tract Sweat glands, Sex organs, Blood vessels Muscarinic Responses by location - Correct Answer a) Eye: Contraction of ciliary muscle focuses lens for near vision. Contraction of iris sphincter causes miosis (constriction) b) Heart: Decreased rate c) Lung: Constriction of bronchi Promotions of secretions d) Bladder: Detrusor contraction increases bladder pressure Relaxation of trigone and sphincter allows urine to leave the bladder. Both effects causes voiding of bladder e) GI tract: Salivation, Increased gastric secretion, Increased intestinal tone and motility, Defecation f) Sweat glands: Generalized sweating g) Sex organs: Erection h) Blood vessels: vasodilation Alpha 1 Locations - Correct Answer Eye, Arterioles (Skin, viscera, mucus membranes), Veins, Sex organs, Prostatic capsule, Bladder Alpha 1 Response by location - Correct Answer - Eye: Mydriasis (dilation) - Arterioles (Skin, viscera, mucus membranes): Constriction - Veins: Constriction - Sex organs, male: Ejaculation