complete
Brevital (Sodium Methohexital)
Primary anesthetic agent introduced in the 1960's.
Balanced Anesthesia
Use of several agents together
Basic Requisites of an Anesthetic
Lack of toxicity, non-flammable, non-addictive, minimal allergenicity.
Analgesia
Given to feel no pain (ex: Fentanyl and Local)
Amnesia
Benzodiazepines (ex: Versed)
Relaxation & Immobility
Versed, Propofol (Diprivan), Brevital (Methohexital), Ketamine
Loss of Consciousness (Hypnosis)
Propofol & Brevital
Wakefulness System
Core of brainstem, neurons to cerebrum. When a sleep inducing drug is introduced it
interrupts transmission.
Anxiolytic (Anxiety Reducing) Meds
Diazepam or Midazolam
Relay Center
Sensory neurons that sense pain pass through this.
Homeostasis (Homeostatic State)
Normal state in which there is minimal variation in respiration and circulation.
Pharmacokinetics
The effects that the body has on drugs.
Pharmacodynamics
The effects that the drug has on various body systems.
Rapid Redistribution
Short acting drug only remain attached to the receptor sites for a short time and then
move to the other tissues.
PO (per os)
Through the mouth.
(Delayed onset, unpredictable effects, patient compliance, not good when pt in
nauseated)
Subcutaneous (SQ)
Beneath the Skin
(Absorption is somewhat delayed compared to IM or IV)
Intramuscular (IM)
In the muscle
(Unpredictable onset of drug effect, cannot titrate the dose)
Intravenous (IV)
In the vein