REGIS NU641 CLINICAL ADV PHARMACOLOGY FINAL EXAM: COVERING
WEEKS 9 – 15 QUESTIONS WITH 100% CORRECT ANSWERS
Clonodine -Ans>>Has several off-label uses including: alcohol and nicotine withdrawal and post
therapeutic neuralgia
Guanfacine -Ans>>hypertension drug that has also been approved to use for ADHD
Ramelteon (Rozerem) -Ans>>Insomnia med that does not have inverse risk for patients engaging in
activities while somnolent with no memory of having taking pill
Common mistakes practitioners make in treating anxiety disorders -Ans>>General diagnosis and
following up to see if treatment goals are being met
Xanax -Ans>>The benzodiazepine with the greatest likelihood of causing dependency s/t it has a short
half-life
Although a patient sees a neurologist for the management of her partial seizures, why is it important
to know her medication regimen? -Ans>>There are many drug-drug interactions with anticonvulsants
Routine education for patient being treated with levetiracetam (Keppra) for seizures -Ans>>To not
abruptly discontinue Keppra due to risk for withdrawal seizures
What advice you would give a woman who has been on Depakote for seizure and wants to get
pregnant -Ans>>Valproate is a known teratogen but may be taken after the first trimester if necessary
Prior to starting antidepressants, the patient should have lab testing to rule out -
Ans>>hypothyroidism
Cholinergic blockers are used to: -Ans>>Counteract the ERS effects of phenothiazines
Control tremors and relax smooth muscles in Parkinson's Disease
Inhibit the muscarinic action of Ach on bladder muscle
Memantine -Ans>>A drug used to treat Alzheimer's disease but is not an anticholinergic
Verapamil -Ans>>Preventative therapy for cluster headache. Can for treatmetn can use oxygen,
sumbritpan, and lidocraine.
Minocycline (PO) -Ans>>
When prescribing for migraines, patient education includes: -Ans>>Stress reduction and regular sleep
are integral to migraine treatment
Acetaminophen -Ans>>Migraines in pregnancy may be safely treated with this
When are migraines considered cured? -Ans>>There is no known cure
Nonpharmacologic Therapy for tension headache includes: -Ans>>biofeedback, stress management,
massage therapy
Fluoxetine -Ans>>First-line antidepressant for children with major depression between 8 to 17 years
old
SSRIs -Ans>>Contains a black-box warning of suicidal ideation in pediatric and adolescent groups
, Stimulants (methylphenidate or amphetamine salts) -Ans>>Are the most effective therapy and are
generally first line of treatment of ADHD in children unless contraindications exist
Hypercalcemia -Ans>>Pt treated with more than 100 grams per week of topical calcipotriene for
psoriasis need to be monitored for
An adolescent female calls the clinic with concerns that her acne is worse 2 weeks after starting
topical tretinoin. What would be the appropriate care for her? -Ans>>Reassure her that the
worsening of acne is normal and it should improve with continued use
Treatment for Tinea capitis -Ans>>Oral griseofulvin or Biweekly shampoo with selenium sulfide or
ketoconazole for 6 to 8 weeks
Treatment for Tinea corporis and tinea pedis -Ans>>Topical antifungals like miconazole applied twice
daily for 4 weeks
Treatment of Onychomycosis -Ans>>Oral griseofulvin, ketoconazole, itraconazole, or terbinafine for
several months; topical product is ciclopirox 8% (Penlac)
Common treatments and counseling points for scabies -Ans>>Common therapies: permethrin,
ivermectin, crotamiton
For permethrin, apply from the neck down, and leave the medication on for at least eight to 10 hours.
Often, all household members and other close contacts should be treated.
Bedding, clothing, and towels used by infested persons or their household, sexual, and close contacts
(as defined above) anytime during the three days before treatment should be decontaminated by
washing in hot water and drying in a hot dryer, by dry-cleaning, or by sealing in a plastic bag for at
least 72 hours.
Reduces Oral contraceptive efficacy -Ans>>Concomitant use of hepatic enzyme inducers such as
rifampin; barrier methods of contraception should be used as backup
Long-term use of androgens requires specific laboratory monitoring of: -Ans>>Calcium, testosterone,
PSA, liver function, glucose, & lipids
existing pregnancy -Ans>>A contraindication to using the morning after (Plan B) contraceptive for
emergency contraception (EC)
To avoid breakthrough bleeding -Ans>>When a hormonal contraceptive and a hormone replacement
therapy drug are taken together, they should be taken at the same time each day
A progestin-only type of contraceptive -Ans>>Can cause irregular menstrual bleeding during the first
month of use
Effects of estrogen include -Ans>>regulation of the menstrual cycle and maintaining normal skin
structure and blood vessel integrity.
Medroxyprogesterone injection -Ans>>may cause an adverse effect of depression
Older male patients using testosterone replacement therapy (TRT) -Ans>>should have a digital
prostate screening examination at 3 and 6 months after starting therapy
Diarrhea -Ans>>Is not a side effect of anticholinergic therapy for urinary incontinence
antimicrobial efficacy -Ans>>For an uncomplicated UTI in a child, reduced symptoms within 48 hours
is a good indicator of
WEEKS 9 – 15 QUESTIONS WITH 100% CORRECT ANSWERS
Clonodine -Ans>>Has several off-label uses including: alcohol and nicotine withdrawal and post
therapeutic neuralgia
Guanfacine -Ans>>hypertension drug that has also been approved to use for ADHD
Ramelteon (Rozerem) -Ans>>Insomnia med that does not have inverse risk for patients engaging in
activities while somnolent with no memory of having taking pill
Common mistakes practitioners make in treating anxiety disorders -Ans>>General diagnosis and
following up to see if treatment goals are being met
Xanax -Ans>>The benzodiazepine with the greatest likelihood of causing dependency s/t it has a short
half-life
Although a patient sees a neurologist for the management of her partial seizures, why is it important
to know her medication regimen? -Ans>>There are many drug-drug interactions with anticonvulsants
Routine education for patient being treated with levetiracetam (Keppra) for seizures -Ans>>To not
abruptly discontinue Keppra due to risk for withdrawal seizures
What advice you would give a woman who has been on Depakote for seizure and wants to get
pregnant -Ans>>Valproate is a known teratogen but may be taken after the first trimester if necessary
Prior to starting antidepressants, the patient should have lab testing to rule out -
Ans>>hypothyroidism
Cholinergic blockers are used to: -Ans>>Counteract the ERS effects of phenothiazines
Control tremors and relax smooth muscles in Parkinson's Disease
Inhibit the muscarinic action of Ach on bladder muscle
Memantine -Ans>>A drug used to treat Alzheimer's disease but is not an anticholinergic
Verapamil -Ans>>Preventative therapy for cluster headache. Can for treatmetn can use oxygen,
sumbritpan, and lidocraine.
Minocycline (PO) -Ans>>
When prescribing for migraines, patient education includes: -Ans>>Stress reduction and regular sleep
are integral to migraine treatment
Acetaminophen -Ans>>Migraines in pregnancy may be safely treated with this
When are migraines considered cured? -Ans>>There is no known cure
Nonpharmacologic Therapy for tension headache includes: -Ans>>biofeedback, stress management,
massage therapy
Fluoxetine -Ans>>First-line antidepressant for children with major depression between 8 to 17 years
old
SSRIs -Ans>>Contains a black-box warning of suicidal ideation in pediatric and adolescent groups
, Stimulants (methylphenidate or amphetamine salts) -Ans>>Are the most effective therapy and are
generally first line of treatment of ADHD in children unless contraindications exist
Hypercalcemia -Ans>>Pt treated with more than 100 grams per week of topical calcipotriene for
psoriasis need to be monitored for
An adolescent female calls the clinic with concerns that her acne is worse 2 weeks after starting
topical tretinoin. What would be the appropriate care for her? -Ans>>Reassure her that the
worsening of acne is normal and it should improve with continued use
Treatment for Tinea capitis -Ans>>Oral griseofulvin or Biweekly shampoo with selenium sulfide or
ketoconazole for 6 to 8 weeks
Treatment for Tinea corporis and tinea pedis -Ans>>Topical antifungals like miconazole applied twice
daily for 4 weeks
Treatment of Onychomycosis -Ans>>Oral griseofulvin, ketoconazole, itraconazole, or terbinafine for
several months; topical product is ciclopirox 8% (Penlac)
Common treatments and counseling points for scabies -Ans>>Common therapies: permethrin,
ivermectin, crotamiton
For permethrin, apply from the neck down, and leave the medication on for at least eight to 10 hours.
Often, all household members and other close contacts should be treated.
Bedding, clothing, and towels used by infested persons or their household, sexual, and close contacts
(as defined above) anytime during the three days before treatment should be decontaminated by
washing in hot water and drying in a hot dryer, by dry-cleaning, or by sealing in a plastic bag for at
least 72 hours.
Reduces Oral contraceptive efficacy -Ans>>Concomitant use of hepatic enzyme inducers such as
rifampin; barrier methods of contraception should be used as backup
Long-term use of androgens requires specific laboratory monitoring of: -Ans>>Calcium, testosterone,
PSA, liver function, glucose, & lipids
existing pregnancy -Ans>>A contraindication to using the morning after (Plan B) contraceptive for
emergency contraception (EC)
To avoid breakthrough bleeding -Ans>>When a hormonal contraceptive and a hormone replacement
therapy drug are taken together, they should be taken at the same time each day
A progestin-only type of contraceptive -Ans>>Can cause irregular menstrual bleeding during the first
month of use
Effects of estrogen include -Ans>>regulation of the menstrual cycle and maintaining normal skin
structure and blood vessel integrity.
Medroxyprogesterone injection -Ans>>may cause an adverse effect of depression
Older male patients using testosterone replacement therapy (TRT) -Ans>>should have a digital
prostate screening examination at 3 and 6 months after starting therapy
Diarrhea -Ans>>Is not a side effect of anticholinergic therapy for urinary incontinence
antimicrobial efficacy -Ans>>For an uncomplicated UTI in a child, reduced symptoms within 48 hours
is a good indicator of
