BIOCHEM 785 DNA&RNA EXAM QUESTIONS WITH ANSWERS
2022/2023 UPDATE UNIT 4
Question 1 of 11
Which of the following could be a potential ramification of a defective nucleotide excision repair (NER)
pathway?
Thymine dimers would accumulate and increase the probability of developing skin cancer.
Thymine dimers would be fixed by DNA polymerase, increasing the probability of developing skin
cancer.
Thymine dimers, caused by UV light, would be repaired, decreasing the probability of developing
skin cancer.
Thymine dimers would persist, decreasing the probability of developing skin cancer.
Question 2 of 11
A patient has received a large dose of ionizing radiation at his place of employment. Which scenario is
accurate?
The homologous recombination pathway is upregulated and is facilitating the removal of
mismatched bases.
Double-stranded DNA breaks are being repaired by nonhomologous end joining, without the use
of a homologous template.
A string of damaged nucleotides is removed and replaced by a new nucleotide sequence in the base
excision repair pathway.
Ligase removes a single damaged base and replaces it with a new nucleotide.
, BIOCHEM 785 DNA&RNA EXAM QUESTIONS WITH ANSWERS
2022/2023 UPDATE UNIT 4
Question 3 of 11
Immediately following transcription, mRNA must be processed before it is transported to the
cytoplasm to undergo translation. Which statement correctly describes mRNA processing?
mRNA is folded into beta-pleated sheets and alpha helices to produce a mature mRNA sequence.
Introns are spliced out and exons are connected to produce a mature mRNA sequence.
Alternative combinations of introns can be linked together to produce closely related gene products.
Exons are removed and introns are inserted into the mature mRNA sequence.
Question 4 of 11
A point mutation has altered the amino acid sequence of a neuronal tau protein, causing serine (Ser) at
position 202 to be mutated to proline (Pro). Which set of codons below corresponds to this mutation?
Genetic code table ©2019 WGU
TCT to CCT
AGG to CCC
AGA to GGA
CGA to AGG
, BIOCHEM 785 DNA&RNA EXAM QUESTIONS WITH ANSWERS
2022/2023 UPDATE UNIT 4
Question 5 of 11
Which of the following is required for DNA polymerase to replicate template DNA in PCR?
DNA primers
RNA polymerase
RNA primers
tRNA
Question 6 of 11
A portion of the HLA gene and its associated amino acid sequence are shown below. If cytosine is
deleted from codon 101, what will be the resulting amino acid sequence?
Genetic code table©2019 WGU
Glu Pro Cys
Glu Met Leu
Glu His Ala
Asp Ser Tyr
, BIOCHEM 785 DNA&RNA EXAM QUESTIONS WITH ANSWERS
2022/2023 UPDATE UNIT 4
Glu
2022/2023 UPDATE UNIT 4
Question 1 of 11
Which of the following could be a potential ramification of a defective nucleotide excision repair (NER)
pathway?
Thymine dimers would accumulate and increase the probability of developing skin cancer.
Thymine dimers would be fixed by DNA polymerase, increasing the probability of developing skin
cancer.
Thymine dimers, caused by UV light, would be repaired, decreasing the probability of developing
skin cancer.
Thymine dimers would persist, decreasing the probability of developing skin cancer.
Question 2 of 11
A patient has received a large dose of ionizing radiation at his place of employment. Which scenario is
accurate?
The homologous recombination pathway is upregulated and is facilitating the removal of
mismatched bases.
Double-stranded DNA breaks are being repaired by nonhomologous end joining, without the use
of a homologous template.
A string of damaged nucleotides is removed and replaced by a new nucleotide sequence in the base
excision repair pathway.
Ligase removes a single damaged base and replaces it with a new nucleotide.
, BIOCHEM 785 DNA&RNA EXAM QUESTIONS WITH ANSWERS
2022/2023 UPDATE UNIT 4
Question 3 of 11
Immediately following transcription, mRNA must be processed before it is transported to the
cytoplasm to undergo translation. Which statement correctly describes mRNA processing?
mRNA is folded into beta-pleated sheets and alpha helices to produce a mature mRNA sequence.
Introns are spliced out and exons are connected to produce a mature mRNA sequence.
Alternative combinations of introns can be linked together to produce closely related gene products.
Exons are removed and introns are inserted into the mature mRNA sequence.
Question 4 of 11
A point mutation has altered the amino acid sequence of a neuronal tau protein, causing serine (Ser) at
position 202 to be mutated to proline (Pro). Which set of codons below corresponds to this mutation?
Genetic code table ©2019 WGU
TCT to CCT
AGG to CCC
AGA to GGA
CGA to AGG
, BIOCHEM 785 DNA&RNA EXAM QUESTIONS WITH ANSWERS
2022/2023 UPDATE UNIT 4
Question 5 of 11
Which of the following is required for DNA polymerase to replicate template DNA in PCR?
DNA primers
RNA polymerase
RNA primers
tRNA
Question 6 of 11
A portion of the HLA gene and its associated amino acid sequence are shown below. If cytosine is
deleted from codon 101, what will be the resulting amino acid sequence?
Genetic code table©2019 WGU
Glu Pro Cys
Glu Met Leu
Glu His Ala
Asp Ser Tyr
, BIOCHEM 785 DNA&RNA EXAM QUESTIONS WITH ANSWERS
2022/2023 UPDATE UNIT 4
Glu
