M-OU 200 (Research Methods)
FMA 4
CRITIQUE OF A RESEARCH PAPER
Student’s name: E-mail add:
Instructor: MIRANDILLA, MA. ELMA
A. Find a research article which is not in the IMRAD format (Introduction,
Methodology, Results and Discussion). Specify an active retrievable link below:
Title of the research article: A QUANTITATIVE APPROACH TO THE STUDY OF
TRANSPLANTABLE TUMOURS
Source/link: https://www.jstor.org/stable/25374632?read-
now=1&oauth_data=eyJlbWFpbCI6ImppbHluLnZhbGRlekBnbWFpbC5jb20iLCJpbn
N0aXR1dGlvbklkcyI6W119&seq=1
Provide a summary of the article in the IMRAD format. Limit to 500 words.
Introduction
Cancer research has naturally focused on the initial variables in cancergenesis
since the advent of specified experimental procedures in the 19th century. Following
Pasteur's demonstration of infectious illness etiology, the quest for analogous causal
factors for cancer was pursued with vigor at the turn of the century. Numerous attempts
were made to transmit cancers within and between species by inoculating live tumors
or tumor extracts. Some positive results were recorded, particularly in rodents, but the
conditions for success were undefinable and the results unpredictable. What did
become clear was that live cancer cells were required in the inoculum and that the
resultant cancer was truly a graft and not a new growth generated by an infectious
"cancer agent." Historical reviews of this exciting and vital period in cancer research
will be found in Oberling ( 1952), Triolo ( 1964), and Woglom ( 1913, 1929).
The primary goal of this research was to use a quantitative approach to the
study of transplantable tumors. Transplanted tumors to aim directly along such lines
at such a distant objective a complete resolution of the various problem. This study
focuses on how key factors of which tumor survival on frozen state, preparation of
tumor suspensions, effect of dehydration, degree of survival, rate of growth, artificial
intracellular fluid, and observe nuclear and cytoplasmic changes through photo
micrographs.
At present, transplanted cancers have contributed to several aspects of cancer
biology: "progression," host-cancer interactions, cancer viruses, chromosome
morphology, biochemistry. They are the chief test objects for possible therapeutic
agents. Methods for maintaining transplanted tumors are described.
Methodology
Transplanted tumors, rather than "spontaneous" cancers, are the most
commonly used for evaluating the therapeutic efficacy of a wide range of drugs.
Because grafts are readily available in large quantities and under apparently
FMA 4
CRITIQUE OF A RESEARCH PAPER
Student’s name: E-mail add:
Instructor: MIRANDILLA, MA. ELMA
A. Find a research article which is not in the IMRAD format (Introduction,
Methodology, Results and Discussion). Specify an active retrievable link below:
Title of the research article: A QUANTITATIVE APPROACH TO THE STUDY OF
TRANSPLANTABLE TUMOURS
Source/link: https://www.jstor.org/stable/25374632?read-
now=1&oauth_data=eyJlbWFpbCI6ImppbHluLnZhbGRlekBnbWFpbC5jb20iLCJpbn
N0aXR1dGlvbklkcyI6W119&seq=1
Provide a summary of the article in the IMRAD format. Limit to 500 words.
Introduction
Cancer research has naturally focused on the initial variables in cancergenesis
since the advent of specified experimental procedures in the 19th century. Following
Pasteur's demonstration of infectious illness etiology, the quest for analogous causal
factors for cancer was pursued with vigor at the turn of the century. Numerous attempts
were made to transmit cancers within and between species by inoculating live tumors
or tumor extracts. Some positive results were recorded, particularly in rodents, but the
conditions for success were undefinable and the results unpredictable. What did
become clear was that live cancer cells were required in the inoculum and that the
resultant cancer was truly a graft and not a new growth generated by an infectious
"cancer agent." Historical reviews of this exciting and vital period in cancer research
will be found in Oberling ( 1952), Triolo ( 1964), and Woglom ( 1913, 1929).
The primary goal of this research was to use a quantitative approach to the
study of transplantable tumors. Transplanted tumors to aim directly along such lines
at such a distant objective a complete resolution of the various problem. This study
focuses on how key factors of which tumor survival on frozen state, preparation of
tumor suspensions, effect of dehydration, degree of survival, rate of growth, artificial
intracellular fluid, and observe nuclear and cytoplasmic changes through photo
micrographs.
At present, transplanted cancers have contributed to several aspects of cancer
biology: "progression," host-cancer interactions, cancer viruses, chromosome
morphology, biochemistry. They are the chief test objects for possible therapeutic
agents. Methods for maintaining transplanted tumors are described.
Methodology
Transplanted tumors, rather than "spontaneous" cancers, are the most
commonly used for evaluating the therapeutic efficacy of a wide range of drugs.
Because grafts are readily available in large quantities and under apparently
