NR 508 WEEK 6 Quiz (Version 1), NR 508: ADVANCED PHARMACOLOGY, Chamberlain College of Nursing

NR 508 Week 6 Quiz
NR 508: ADVANCED PHARMACOLOGY

, 1. Question : Which disorder is characterized by the formation of abnormal new bone
at an accelerated rate beginning with excessive resorption of spongy
bone?

Student
Answer: Osteomalacia

Paget disease

Osteoporosis

Osteosarcoma
Instructor Paget disease (osteitis deformans) is a state of increased metabolic activity in bone
Explanation: characterized by abnormal and excessive bone remodeling, both resorption and
formation. Chronic accelerated remodeling eventually enlarges and softens the
affected bones.

Points Received: 2 of 2
Comments:



Question 2 Question : Considering the pathophysiology of osteoporosis, what are the effects
. of extracellular signal regulated kinases (ERKs) and receptor activator
of RANKL on osteoblasts and osteoclasts?

Student Answer:
ERKs increase the life span of osteoclasts and RANKL decreases
the life span of osteoblasts.

ERKs and RANKL increase the life span of osteoclasts and
decrease the life span of osteoblasts.

ERKs and RANKL increase the life span of osteoblasts and
decrease the life span of osteoclasts.

ERKs increase the life span of osteoblasts and RANKL decreases
the life span of osteoclasts.
Instructor In addition to ERKs, RANKL is required for the antiapoptotic and thus longer
Explanation: life span of osteoclasts. These effects increase the life span of osteoclasts
(i.e., longer bone resorbing) and shorten the life span of the bone-forming
cells, or osteoblasts.

Points Received: 2 of 2
Comments:



Question 3 Question : _____ is the temporary displacement of two bones in which the bone
. surfaces partially lose contact.