e
(25-
-Blood I ↓warl pi
-
"Blood is
defined as
specialized connective tissue, consisting of ligund interceltulas
elements
plasma formed
"
substance, he i.e the RBC, WBC he
platelets.
↳ known as
"Fluid life"-carries
from lungs to body 4CO2 from body to lungs
O
·
of
nutritive substances
of growth"-carries system by hormones from
"Fluid
from digestive endocrine
·
all tissues.
system
to
"Find
·
of health"-protects body againstdiseases getrid of unwanted substances by
them
transporting to
kidneys.
=>
average volume
of blood in a normal adult 52(4.52inq)
in
=>
newborn 450 me
->
8%
of body weightof young healthy adult
weighing 20
kg
·
Composition of Blood
-
plasma (55%)-a straw colored clear liquid partof blood.
-
formed elements (45%)
·
Seum
↳ a clear straw colored
fluid that
blood clot. abt 45min,
oozes from After
clot.
S
sum
oozes out
of blood
-
volume
of seven almost same
is as
that of plasma i.055%
-
SERUM:PLASMA:FIBRINOGEN
-
· Function of Blood:
1. Nutritive function (transportof A.A, glucose, lipids vitamine)
2.
Respiratory function (transportof O2 4CO2)
3. Excretory
function (transportof products)
waste
Storage function (water, proteins, glucose, sodium 4 potassium storage)
-
4.
I
(by WBCs)
S
5.
Defensure function
6.
Transport of hormones by enzymes
interstitial fluid)
7. of
Regulation water balance (water content
freely interchangeable with
8.
Regulation of by Ab act
acid-base balance (Plasma
proteins as
bufferl/
9.
of body temperature
Regulation (bar specific
of high heat of blood)
10. Plasma preventfrom
proteins edema
at
formation of injury.
Platelets 4 site
clotting factor
cure lot
·
of blood:
Formation
1 microliteBlood
· 5M RBC in Volume
·
of RBL expressed in 1.
15g Hb/100me of
· Blood in Male (bcz of absence
of estrogen is called Hematocrit value or
·
149 Hb/100ml of Blood in Female. I presence of testosterone) PCU (Packed all volumes
About WBC's in 1 incrolite blood
·
7000 of
· Abt 150,000 450,000
to Platelets
in 1 microlite of blood.
, Plasma Proteins
-
all
·
plasma proteins are
formed in exceptgamma
liver
globulins which are
formed in lymphocytes.
Albumin-major protein, maintains
1)
osmolarity
the
deficiency
of blood bits lead
pitting
to edema.
2) Ceruloplasmin-contain is an its
deficiency in Willow Disease.
occur
Renal Failure.
3) Haptoglobin-binds with
free It is preventfrom
with preventiron loss.
4) Hemoplexin-bind free Harm he
Fetoprotein level increase in Liver
its carcinoma
5) Alpha 1 -
deficiency leads to
Emphysema which due
smoking.
Antitrypsin
- occur
6) Alpha
to
1
7) complementproteins
- are
partof immunity
innate by helps in
phagocytosis of pathogens.
8) Clotting factors
-
help in Blood
clotting atsite of injury
at
clot formation site
of injury.
in
9) Fibrinogen -
helps
antibodies
10) Gamma Globulins -
like
protect from pathogens
·
Biosynthesis:
I lives
Lymphocyte
=>
immunoglobulin)
B-48)
enterocyte (apoprotein
->
·
most abundantplasma protein
is albumin, then
IgG.
· Functions:
colloid
1) Maintain osmotic all proteins but albumin.
pressure -
by 70%
by
viscosity
Maintain -
viscosity
of blood is maintained
by RBC by that
of plasma is maintained by plasma proteins globulin.
especially
Maintain blood pressure maintanance
3) -
viscosity is
imp factor
in
of B.P.
2) Blood Clotting -
by Fibrinogen 4 prothrombin
5) Actas antibodies -
Gamma Globalin which protectbody from infections.
various
6) Maintain
ESR-chiefly by fibrinogen, less by globulin is least
by albumin
7) Transportof substances steroids etc
- like bilirubins, drugs, hormones 4
8) Transportof CO2- small
age is
transported as combined
with called
plane proteins carbamino proteins.
4) Act proteinreserve-from draw starvation
which
during
proteins
as tissues can
1) Maintain
acid-base balance-due hence
amino acids
to acts
as
buffer.
1) Role in
stability
suspension of by globulin by fibrinogen
RBCs -
·
patientwith LD, menal failure will present
12) Role in
of
production trephone subs-necessary for nourishmentof with
deficiency of plasma protein and
Tissue cells in
culture
edema.
produced by leukocytes is
albumin smaller than
Plasma proteins pores of glomerular
from membrane but
still
they are not
filtered
because
of we
charge he in renal
disease, itgets filtered outby appears
in urine.
(25-
-Blood I ↓warl pi
-
"Blood is
defined as
specialized connective tissue, consisting of ligund interceltulas
elements
plasma formed
"
substance, he i.e the RBC, WBC he
platelets.
↳ known as
"Fluid life"-carries
from lungs to body 4CO2 from body to lungs
O
·
of
nutritive substances
of growth"-carries system by hormones from
"Fluid
from digestive endocrine
·
all tissues.
system
to
"Find
·
of health"-protects body againstdiseases getrid of unwanted substances by
them
transporting to
kidneys.
=>
average volume
of blood in a normal adult 52(4.52inq)
in
=>
newborn 450 me
->
8%
of body weightof young healthy adult
weighing 20
kg
·
Composition of Blood
-
plasma (55%)-a straw colored clear liquid partof blood.
-
formed elements (45%)
·
Seum
↳ a clear straw colored
fluid that
blood clot. abt 45min,
oozes from After
clot.
S
sum
oozes out
of blood
-
volume
of seven almost same
is as
that of plasma i.055%
-
SERUM:PLASMA:FIBRINOGEN
-
· Function of Blood:
1. Nutritive function (transportof A.A, glucose, lipids vitamine)
2.
Respiratory function (transportof O2 4CO2)
3. Excretory
function (transportof products)
waste
Storage function (water, proteins, glucose, sodium 4 potassium storage)
-
4.
I
(by WBCs)
S
5.
Defensure function
6.
Transport of hormones by enzymes
interstitial fluid)
7. of
Regulation water balance (water content
freely interchangeable with
8.
Regulation of by Ab act
acid-base balance (Plasma
proteins as
bufferl/
9.
of body temperature
Regulation (bar specific
of high heat of blood)
10. Plasma preventfrom
proteins edema
at
formation of injury.
Platelets 4 site
clotting factor
cure lot
·
of blood:
Formation
1 microliteBlood
· 5M RBC in Volume
·
of RBL expressed in 1.
15g Hb/100me of
· Blood in Male (bcz of absence
of estrogen is called Hematocrit value or
·
149 Hb/100ml of Blood in Female. I presence of testosterone) PCU (Packed all volumes
About WBC's in 1 incrolite blood
·
7000 of
· Abt 150,000 450,000
to Platelets
in 1 microlite of blood.
, Plasma Proteins
-
all
·
plasma proteins are
formed in exceptgamma
liver
globulins which are
formed in lymphocytes.
Albumin-major protein, maintains
1)
osmolarity
the
deficiency
of blood bits lead
pitting
to edema.
2) Ceruloplasmin-contain is an its
deficiency in Willow Disease.
occur
Renal Failure.
3) Haptoglobin-binds with
free It is preventfrom
with preventiron loss.
4) Hemoplexin-bind free Harm he
Fetoprotein level increase in Liver
its carcinoma
5) Alpha 1 -
deficiency leads to
Emphysema which due
smoking.
Antitrypsin
- occur
6) Alpha
to
1
7) complementproteins
- are
partof immunity
innate by helps in
phagocytosis of pathogens.
8) Clotting factors
-
help in Blood
clotting atsite of injury
at
clot formation site
of injury.
in
9) Fibrinogen -
helps
antibodies
10) Gamma Globulins -
like
protect from pathogens
·
Biosynthesis:
I lives
Lymphocyte
=>
immunoglobulin)
B-48)
enterocyte (apoprotein
->
·
most abundantplasma protein
is albumin, then
IgG.
· Functions:
colloid
1) Maintain osmotic all proteins but albumin.
pressure -
by 70%
by
viscosity
Maintain -
viscosity
of blood is maintained
by RBC by that
of plasma is maintained by plasma proteins globulin.
especially
Maintain blood pressure maintanance
3) -
viscosity is
imp factor
in
of B.P.
2) Blood Clotting -
by Fibrinogen 4 prothrombin
5) Actas antibodies -
Gamma Globalin which protectbody from infections.
various
6) Maintain
ESR-chiefly by fibrinogen, less by globulin is least
by albumin
7) Transportof substances steroids etc
- like bilirubins, drugs, hormones 4
8) Transportof CO2- small
age is
transported as combined
with called
plane proteins carbamino proteins.
4) Act proteinreserve-from draw starvation
which
during
proteins
as tissues can
1) Maintain
acid-base balance-due hence
amino acids
to acts
as
buffer.
1) Role in
stability
suspension of by globulin by fibrinogen
RBCs -
·
patientwith LD, menal failure will present
12) Role in
of
production trephone subs-necessary for nourishmentof with
deficiency of plasma protein and
Tissue cells in
culture
edema.
produced by leukocytes is
albumin smaller than
Plasma proteins pores of glomerular
from membrane but
still
they are not
filtered
because
of we
charge he in renal
disease, itgets filtered outby appears
in urine.
