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Fertilization of egg and sperm

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A comprehensive document containing basic information of Fertilization of egg and sperm , its phases and results in a diagrammatic format easy to understand and comprehend and written by your fellow medical student.

Institution
Course

Content preview

uterus
body of
in




ELIZATION -m
ocus
·
capacitation
is acrosome rex
appeal
to be regulated
by a
tyrosine
kinare, Sc kinase.




wd sequenceofmolecularweallularproces
#


intermngig of
which
of e
mate

beginswith
contact
the
with
south
by span by ends




=> most
usually occurs in
ampulla,
the takes
approximately 24 hours. ↳ ovum is a nourmotile cell be

so iti s
broughtinto the
uterine

conditions take
for
=>


sperm to
fertilize, two must be
followed: through I
ways:


capacitation(conditioning
rex)
1) by sweeping action
of fimbrias

↳ acrosomal rex
c) by fluid currents
produced
by ciliaof mucosal cells
·
capacitation:
of fimbrias.
- head
washing
- take 7 hours


-
done
by enzymes from mucosal
lining
of uterine tube.


radiata to
-



capacitated
sperms can
pass through colona bird to
zona pellucida (2p*)
proteins
Acrosomal
· rex:


- starts
as soon as
sperm binds/touches the
zp" proteins.
in
also assist
span)
meter
created

directalle
are in membrane of
apertures plasma sperm
-
-




-


enzymes are released to
digestzona a
pellucid umonaljail
of
of
corona


Mi-movement
ebal
↳ acrosin (a proteolytic
enzyme)
↳ trypsin like peristaltic
=>
movements
of fimbrial
↳ hyalmonidases (disposal of follicular cells of corona radiata he zona
pellucidal more the oven in the iteline

tube.
↳ exterase

↳ neuaminidase
·
tic:
cell the
containing
head
- lost autorial
his
partof in acosomal rex in a a male he
female pronuclei

which
I
so
·
proximal part of spam
the membrane
fuses with the
orcyte membrane by not
are
fusing
the
frontpart. when fused ->
Tygate
induced
·
acrosomal rex is
by zone

·
ovum survives
for only 1-2(max)

zonal cortical days as in bow this
time
if
it
=>

sex:


-
otters
zona structure
he inactivates
specie specificreceptor
sites release
by of lysosomal enzyme
doesn't
getfertilized i tdies.
then

cortical
by granules in
space.
perivitelline survives atleast 48
sperm for
·




the arrival days.
As on
of sperm ine it touches the membrane,
oocyte there
a re 3
responses
hours to
many
the orum:
by
I

of
23 chr
-
cortical sex



prone
plug presenti n the
- mucous
=>
curixcanal

of 2nd
completion meiotic division
nucleus
-




a e become thin
by less viscous by stringy.
-
increased metabolic
activity
of egg. ↓
indicator
that

its
without plasma membrane.
speime enter
in
cytoplasm of oxcyte femaleene
-> a




RESULTS OF FERTILIZATION:

-maintenance
of diploid number
of Chr
sperm may take
=>
5minutes (min) -
45min
-
establishment of sex.

(max) ampulla cervix
from
to
reach
- metabolic activation
of zygote by initiation of cleavage.
=>
spelme slow down at isthmus and
stimulates
penetrated 2nd meiotic
occyte complete
to
-




results division. speed up by sensing
chemo
-
in variation of human
species attractants radiata
from corona

through mingling
of maternal by paternal chromosomes.
all ovulated ovum.
-




of

Written for

Institution
Course

Document information

Uploaded on
May 14, 2023
Number of pages
2
Written in
2022/2023
Type
Class notes
Professor(s)
Prof. dr. zach murphy
Contains
Mbbs, embryology

Subjects

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