Chhattisgarh Swami Vivekanand Technical University, Bhilai (C.G.)
Scheme of Teaching and Examination
Bachelor of Pharmacy (B. Pharmacy)
V– Semester
Internal Assessment End Semester Exams
S. Board of Name of the course Total Credit
Continuous Sessional Exams Marks
No Study Subject Code with PCI code Total Marks Duration
Mode Marks Duration
Medicinal Chemistry – II – Theory tinuous
1. Pharmacy 341551 (41) M1o0de 15 1 Hr 25 75 3 Hrs 100 4
(BP501T)
Formulative Pharmacy – Theory
2. Pharmacy 341552 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
(BP502T)
Pharmacology – II – Theory
3. Pharmacy 341553 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
(BP503T)
Pharmacognosy – II – Theory
4. Pharmacy 341554 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
(BP504T)
Pharmaceutical Jurisprudence –
5. Pharmacy 341555 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
Theory (BP505T)
Formulative Pharmacy – Practical
6. Pharmacy 341561 (41) 5 10 4 Hr 15 35 4 Hrs 50 2
(BP506P)
Pharmacology – II – Practical
7. Pharmacy 341562 (41) 5 10 4 Hr 15 35 4 Hrs 50 2
(BP507P)
Pharmacognosy – II – Practical
8. Pharmacy 341563 (41) 5 10 4 Hr 15 35 4 Hrs 50 2
(BP508P)
Total 65 105 17 Hr 170 480 27 Hrs 650 26
,CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI (C.G.)
Semester: B. Pharmacy 5th semester Branch: Pharmacy
Subject: Medicinal Chemistry – II – Theory (BP501T) Subject Code: 341551 (41)
Total Theory Periods: 45 Total Tutorial Periods: 15
Total Marks in the End Semester: 75
Minimum of Class tests to be conducted: 02
45 Hours
Scope: This subject is designed to impart fundamental knowledge on the structure,chemistry and
therapeutic value of drugs. The subject emphasizesstructure activity relationships of drugs,
theimportance of physicochemical properties and metabolism of drugs. The syllabus also emphasizes on
thechemical synthesis of important drugs under each class.
Objectives: Upon completion of the course the student shall be able to
1. Understand the chemistry of drugs with respect to their pharmacological activity
2. Understand the drug metabolic pathways, adverse effect and therapeutic value of drugs
3. Know the Structural Activity Relationship of different class of drugs
4. Study the chemical synthesis of selected drugs
Course Content:
Study of the development of the following classes of drugs, Classification, mechanism of
action, uses of drugs mentioned in the course, Structure-activity relationship of selective
class of drugs as specified in the course and synthesis of drugs superscripted (*)
UNIT- I 10 Hours
Antihistaminic agents: Histamine, receptors and their distribution in the human body
H1–antagonists: Diphenhydramine hydrochloride*, Dimenhydrinate,Doxylamines
cuccinate, Clemastine fumarate, Diphenylphyraline hydrochloride, Tripelenamine
hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine
hydrochloride, Chlorpheniramine maleate, Triprolidine
hydrochloride*, Phenidamine tartarate, Promethazine hydrochloride*, Trimeprazine
tartrate, Cyproheptadine hydrochloride, Azatidine maleate, Astemizole, Loratadine,
Cetirizine, Levocetrazine Cromolyn sodium
H2-antagonists: Cimetidine*, Famotidine, Ranitidin.
Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole,Pantoprazole
Anti-neoplastic agents:
Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan,
-2-
, Chlorambucil, Busulfan, Thiotepa
Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil,
Floxuridine,Cytarabine, Methotrexate*, Azathioprine
Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin
Plant products: Etoposide, Vinblastin sulphate, Vincristine sulphate
Miscellaneous: Cisplatin, Mitotane.
UNIT – II 10 Hours
Anti-anginal:
Vasodilators: Amyl nitrite, Nitroglycerin*, Pentaerythritol tetranitrate,
Isosorbidedinitrite*, Dipyridamole.
Calcium channel blockers: Verapamil, Bepridil hydrochloride,
Diltiazemhydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine,
Nimodipine.
Diuretics:
Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide,
Dichlorphenamide.
Thiazides: Chlorothiazide*, Hydrochlorothiazide, Hydroflumethiazide,
Cyclothiazide,
Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid.
Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride.
Osmotic Diuretics: Mannitol
Anti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril,
Benazeprilhydrochloride, Quinapril hydrochloride, Methyldopate hydrochloride,*
Clonidine hydrochloride, Guanethidine monosulphate, Guanabenz acetate, Sodium
nitroprusside, Diazoxide, Minoxidil, Reserpine, Hydralazine hydrochloride.
UNIT- III 10 Hours
Anti-arrhythmic Drugs: Quinidine sulphate, Procainamide
hydrochloride,Disopyramide phosphate*, Phenytoin sodium, Lidocaine
hydrochloride, Tocainide hydrochloride, Mexiletine hydrochloride, Lorcainide
hydrochloride, Amiodarone, Sotalol.
Anti-hyperlipidemic agents: Clofibrate, Lovastatin, Cholesteramine
andCholestipol
Coagulant & Anticoagulants: Menadione, Acetomenadione,
Warfarin*,Anisindione, clopidogrel
Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide,
Bosentan, Tezosentan.
-3-
Scheme of Teaching and Examination
Bachelor of Pharmacy (B. Pharmacy)
V– Semester
Internal Assessment End Semester Exams
S. Board of Name of the course Total Credit
Continuous Sessional Exams Marks
No Study Subject Code with PCI code Total Marks Duration
Mode Marks Duration
Medicinal Chemistry – II – Theory tinuous
1. Pharmacy 341551 (41) M1o0de 15 1 Hr 25 75 3 Hrs 100 4
(BP501T)
Formulative Pharmacy – Theory
2. Pharmacy 341552 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
(BP502T)
Pharmacology – II – Theory
3. Pharmacy 341553 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
(BP503T)
Pharmacognosy – II – Theory
4. Pharmacy 341554 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
(BP504T)
Pharmaceutical Jurisprudence –
5. Pharmacy 341555 (41) 10 15 1 Hr 25 75 3 Hrs 100 4
Theory (BP505T)
Formulative Pharmacy – Practical
6. Pharmacy 341561 (41) 5 10 4 Hr 15 35 4 Hrs 50 2
(BP506P)
Pharmacology – II – Practical
7. Pharmacy 341562 (41) 5 10 4 Hr 15 35 4 Hrs 50 2
(BP507P)
Pharmacognosy – II – Practical
8. Pharmacy 341563 (41) 5 10 4 Hr 15 35 4 Hrs 50 2
(BP508P)
Total 65 105 17 Hr 170 480 27 Hrs 650 26
,CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI (C.G.)
Semester: B. Pharmacy 5th semester Branch: Pharmacy
Subject: Medicinal Chemistry – II – Theory (BP501T) Subject Code: 341551 (41)
Total Theory Periods: 45 Total Tutorial Periods: 15
Total Marks in the End Semester: 75
Minimum of Class tests to be conducted: 02
45 Hours
Scope: This subject is designed to impart fundamental knowledge on the structure,chemistry and
therapeutic value of drugs. The subject emphasizesstructure activity relationships of drugs,
theimportance of physicochemical properties and metabolism of drugs. The syllabus also emphasizes on
thechemical synthesis of important drugs under each class.
Objectives: Upon completion of the course the student shall be able to
1. Understand the chemistry of drugs with respect to their pharmacological activity
2. Understand the drug metabolic pathways, adverse effect and therapeutic value of drugs
3. Know the Structural Activity Relationship of different class of drugs
4. Study the chemical synthesis of selected drugs
Course Content:
Study of the development of the following classes of drugs, Classification, mechanism of
action, uses of drugs mentioned in the course, Structure-activity relationship of selective
class of drugs as specified in the course and synthesis of drugs superscripted (*)
UNIT- I 10 Hours
Antihistaminic agents: Histamine, receptors and their distribution in the human body
H1–antagonists: Diphenhydramine hydrochloride*, Dimenhydrinate,Doxylamines
cuccinate, Clemastine fumarate, Diphenylphyraline hydrochloride, Tripelenamine
hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine
hydrochloride, Chlorpheniramine maleate, Triprolidine
hydrochloride*, Phenidamine tartarate, Promethazine hydrochloride*, Trimeprazine
tartrate, Cyproheptadine hydrochloride, Azatidine maleate, Astemizole, Loratadine,
Cetirizine, Levocetrazine Cromolyn sodium
H2-antagonists: Cimetidine*, Famotidine, Ranitidin.
Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole,Pantoprazole
Anti-neoplastic agents:
Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan,
-2-
, Chlorambucil, Busulfan, Thiotepa
Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil,
Floxuridine,Cytarabine, Methotrexate*, Azathioprine
Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin
Plant products: Etoposide, Vinblastin sulphate, Vincristine sulphate
Miscellaneous: Cisplatin, Mitotane.
UNIT – II 10 Hours
Anti-anginal:
Vasodilators: Amyl nitrite, Nitroglycerin*, Pentaerythritol tetranitrate,
Isosorbidedinitrite*, Dipyridamole.
Calcium channel blockers: Verapamil, Bepridil hydrochloride,
Diltiazemhydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine,
Nimodipine.
Diuretics:
Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide,
Dichlorphenamide.
Thiazides: Chlorothiazide*, Hydrochlorothiazide, Hydroflumethiazide,
Cyclothiazide,
Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid.
Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride.
Osmotic Diuretics: Mannitol
Anti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril,
Benazeprilhydrochloride, Quinapril hydrochloride, Methyldopate hydrochloride,*
Clonidine hydrochloride, Guanethidine monosulphate, Guanabenz acetate, Sodium
nitroprusside, Diazoxide, Minoxidil, Reserpine, Hydralazine hydrochloride.
UNIT- III 10 Hours
Anti-arrhythmic Drugs: Quinidine sulphate, Procainamide
hydrochloride,Disopyramide phosphate*, Phenytoin sodium, Lidocaine
hydrochloride, Tocainide hydrochloride, Mexiletine hydrochloride, Lorcainide
hydrochloride, Amiodarone, Sotalol.
Anti-hyperlipidemic agents: Clofibrate, Lovastatin, Cholesteramine
andCholestipol
Coagulant & Anticoagulants: Menadione, Acetomenadione,
Warfarin*,Anisindione, clopidogrel
Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide,
Bosentan, Tezosentan.
-3-
