NURS 660 EXAM 3 questions with complete solutions
What is the medication that is the antidote for alprazolam?
flumazenil
What is the MOA of pregabalin that makes it alleviate pain for people with
fibromyalgia or chronic fatigue?
binds to the alpha 2 delta sub-units of voltage sensitive calcium channels
What is an antagonist of caffeine
adenosine
Diagnose this pt: Patient comes in with a CC of anxiety. She has been excessively
worrying, increased arousal, increased tiredness and irritability. What is the
primary and least likely diagnosis?
GAD; Panic Disorder
Somebody w/ anxiety worries about having a panic attack, in addition has mood
changes to avoid things in order to not have a panic attack.
Panic disorder
A woman was raped, and continues to have fear of opposite sex on her way to
parking garage. Which two areas of the brain are involved?
amygdala and hippocampus
MOA of modafinil (Provigil). How does it promote normal wakefulness
histamine, NE at alpha adrenergic receptor sites, dopamine at D2 receptors
What is the MOA of eszopiclone? What receptors does it act on?
Binds to GABA receptors to increase GABA to increase sleepiness
Which would be the first line appropriate pharmacological agent for PTSD?
Paroxetine
What mediation is used to alleviate to help cognitive pain and physical symptoms
in fibromyalgia?
Milnacepran (Savella)
With the difficulty breathing is related hypothetically to the activation of what area
of the brain?
parabrachial nucleous
What medications are good for falling asleep "sleep induction" and are not
addictive?
Suvorexant (Belsmora)
Know the MOA of buspirone. Which receptor does it primarily act upon?
serotonin 1a 5HT1A partial agonist
How does melatonin improve sleep? What receptors does it act on? Agonist or
antatonist?
Secreted by the pineal glad to attach to receptors in the suprachiasmic nucleus to
regulate the circadian rhythm; agonist
Current dx of generalized anxiety disorder (GAD), difficulty concentrating as well
as problems falling asleep. She gets very angry over basic things and is very
moody in general, excessive stressful reactions, concentrate, irritability. What is
going on in her brain?
a. Dysfunction of amygdale and CTSC (serotonin/nor-einephrine)
What is the medication that is the antidote for alprazolam?
flumazenil
What is the MOA of pregabalin that makes it alleviate pain for people with
fibromyalgia or chronic fatigue?
binds to the alpha 2 delta sub-units of voltage sensitive calcium channels
What is an antagonist of caffeine
adenosine
Diagnose this pt: Patient comes in with a CC of anxiety. She has been excessively
worrying, increased arousal, increased tiredness and irritability. What is the
primary and least likely diagnosis?
GAD; Panic Disorder
Somebody w/ anxiety worries about having a panic attack, in addition has mood
changes to avoid things in order to not have a panic attack.
Panic disorder
A woman was raped, and continues to have fear of opposite sex on her way to
parking garage. Which two areas of the brain are involved?
amygdala and hippocampus
MOA of modafinil (Provigil). How does it promote normal wakefulness
histamine, NE at alpha adrenergic receptor sites, dopamine at D2 receptors
What is the MOA of eszopiclone? What receptors does it act on?
Binds to GABA receptors to increase GABA to increase sleepiness
Which would be the first line appropriate pharmacological agent for PTSD?
Paroxetine
What mediation is used to alleviate to help cognitive pain and physical symptoms
in fibromyalgia?
Milnacepran (Savella)
With the difficulty breathing is related hypothetically to the activation of what area
of the brain?
parabrachial nucleous
What medications are good for falling asleep "sleep induction" and are not
addictive?
Suvorexant (Belsmora)
Know the MOA of buspirone. Which receptor does it primarily act upon?
serotonin 1a 5HT1A partial agonist
How does melatonin improve sleep? What receptors does it act on? Agonist or
antatonist?
Secreted by the pineal glad to attach to receptors in the suprachiasmic nucleus to
regulate the circadian rhythm; agonist
Current dx of generalized anxiety disorder (GAD), difficulty concentrating as well
as problems falling asleep. She gets very angry over basic things and is very
moody in general, excessive stressful reactions, concentrate, irritability. What is
going on in her brain?
a. Dysfunction of amygdale and CTSC (serotonin/nor-einephrine)
