PATHO 370 Quiz 1 - With Correct Answers and Feedback
Elaborations
Question 1I
• 0.125 Iout Iof I0.125 Ipoints
Your Ipatient Ieats I“lots Iof Ifat,” Ileads Ia I“stressful” Ilife, Iand Ihas Ismoked I“about Itwo
Ipacks Ia Iday Ifor Ithe Ilast I40 Iyears.” IHer Ichronic Imorning Icough Irecently Iworsened, Iand
Ishe Iwas Idiagnosed Iwith Ia Ilung Imass. IThe Imost Ilikely Icontributing Ifactor Ifor
Idevelopment Iof Ilung Icancer Iin Ithis Ipatient Iis
Selected IAnswer: b. Icigarette Ismoking.
CI orrect IAnswer: b. Icigarette Ismoking.
Response
IFeedbac
The Imost Ilikely Icontributing Ifactor Ifor Ithe Idevelopment Iof Ilung Icancer Iis
Icigarette Ismoking. ITobacco Ismoke Icontains Ihundreds Iof Icompounds, Imany
k
Iof Iwhich Ihave Iknown Igenotoxicity Iand Iprobably Iserve Ias Iinitiators. ITobacco
:
Ismoke Ialso Icontains Ipromoters, Iwhich Ispur Ithe Imutant Icells Ito Iproliferate.
IAlthough Ia Ihigh-fat Idiet, Iurban Ipollutants, Iand Ia Istressful Ilifestyle Ihave
Ibeen Iimplicated Iin Isome Itypes Iof Icancer, Ithey Iare Inot Ithe Ilikely
Icontributing Ifactor Iin Iyour Ipatient’s Ilung Icancer.
1. Question 2
I I
• 0.125 Iout Iof I0.125 Ipoints
Many Iof Ithe Iresponses Ito Istress Iare Iattributed Ito Iactivation Iof Ithe Isympathetic Inervous
IsystemIand
Iare Imediated Iby
Selected IAnswer: b. Inorepinephrine.
CI orrect IAnswer: b. Inorepinephrine.
Response
Norepinephrine Iis Isecreted Iin Iresponse Ito Iactivation Iof Ithe Isympathetic
IFeedbac
Inervous sI ystem Iduring Istress Iby Ithe Iadrenal Imedulla. ICortisol Iis Isecreted
k
Iby Ithe Iadrenal cI ortex. IGlucagon Iis Isecreted Iby Ithe Ipancreas. IACTH Iis
:
Isecreted Iby Ithe Ipituitary gI land.
1. Question 3
I I
• 0.125 Iout Iof I0.125 Ipoints
The Inurse Iis Iswabbing Ia Ipatient’s Ithroat Ito Itest Ifor Istreptococcal Ipharyngitis. IThe Inurse
Imust Iunderstand Ithat Itests Isuch Ias Ithis Idiffer Iin Ithe Iprobability Ithat Ithey Iwill Ibe Ipositive
Ifor Ia Icondition Iwhen Iapplied Ito Ia Iperson Iwith Ithe Icondition; Ithis Iprobability Iis Itermed
Isensitivity.
Selected IAnswer: b.
,I True CI orrect IAnswer:
b. ITrue
Response The Isensitivity Iof Iany Itest Irefers Ito Ithe Iprobability Ithat Ithe Itest Iwill Ibe
Ipositive
, Feedback: when Iapplied Ito Ia Iperson Iwith Ithe Icondition Iand Iwill Inot Iprovide Ia
Ifalse Inegative Iresult. IIn Icontrast, Ispecificity Iis Ithe Iprobability Ithat Ia
Itest Iwill Ibe Inegative Iwhen Iapplied Ito Ia Iperson Iwho Idoes Inot Ihave Ia
Igiven Icondition.
1. Question 4
I I
• 0.125 Iout Iof I0.125 Ipoints
All Ithese Icellular Iresponses Iare Ipotentially Ireversible Iexcept
Selected IAnswer: b. Inecrosis.
CI orrect IAnswer: b. Inecrosis.
Response
IFeedbac
Necrosis Irefers Ito Ideath Iof Icells/tissue Iand Iis Inot Ireversible. IMetaplasia
Irefers Ito tI he Ireplacement Iof Ione Idifferentiated Icell Itype Iwith Ianother Ifrom
k
Ipersistent Iinjury Iand Iis Ireversible Iwhen Ithe Iinjury Istops. IAtrophy Ioccurs
:
Ibecause Iof Ilack Iof Iuse Iof Ian Iorgan Iand Iis Ireversible. IHyperplasia Iis Ian
Iincrease Iin Ithe Inumber Iof Icells Ifrom Iincreased Iphysiologic Idemands Ior
Ihormonal Istimulation Iand Iis Ireversible.
1. Question 5
I I
• 0.125 Iout Iof I0.125 Ipoints
Coagulative Inecrosis Iis Icaused
I by
Selected IAnswer: a. Iinterrupted Iblood Isupply.
CI orrect IAnswer: a. Iinterrupted Iblood Isupply.
Response
IFeedbac
Coagulative Inecrosis Iresults Ifrom Iinterrupted Iblood Isupply Ileading Ito
Iischemic cI ell Iinjury. ILiquefactive Inecrosis Iresults Ifrom Idissolving Iof Idead
k
Icells Iand Icyst Iformation. IFat Inecrosis Iis Icaused Iby Itrauma Ior Ipancreatitis.
:
ICaseous Inecrosis Iis Icaused Iby Ilung Itissue Idamage Isuch Ias Ithat Icaused Iby
Ituberculosis.
1. Question 6
I I
• 0.125 Iout Iof I0.125 Ipoints
The Imost Icommon Itumor-suppressor Igene Idefect Iidentified Iin Icancer Icells Iis
SI elected IAnswer: c. IP53.
Correct IAnswer: c. IP53.
Response k
IFeedbac :
Elaborations
Question 1I
• 0.125 Iout Iof I0.125 Ipoints
Your Ipatient Ieats I“lots Iof Ifat,” Ileads Ia I“stressful” Ilife, Iand Ihas Ismoked I“about Itwo
Ipacks Ia Iday Ifor Ithe Ilast I40 Iyears.” IHer Ichronic Imorning Icough Irecently Iworsened, Iand
Ishe Iwas Idiagnosed Iwith Ia Ilung Imass. IThe Imost Ilikely Icontributing Ifactor Ifor
Idevelopment Iof Ilung Icancer Iin Ithis Ipatient Iis
Selected IAnswer: b. Icigarette Ismoking.
CI orrect IAnswer: b. Icigarette Ismoking.
Response
IFeedbac
The Imost Ilikely Icontributing Ifactor Ifor Ithe Idevelopment Iof Ilung Icancer Iis
Icigarette Ismoking. ITobacco Ismoke Icontains Ihundreds Iof Icompounds, Imany
k
Iof Iwhich Ihave Iknown Igenotoxicity Iand Iprobably Iserve Ias Iinitiators. ITobacco
:
Ismoke Ialso Icontains Ipromoters, Iwhich Ispur Ithe Imutant Icells Ito Iproliferate.
IAlthough Ia Ihigh-fat Idiet, Iurban Ipollutants, Iand Ia Istressful Ilifestyle Ihave
Ibeen Iimplicated Iin Isome Itypes Iof Icancer, Ithey Iare Inot Ithe Ilikely
Icontributing Ifactor Iin Iyour Ipatient’s Ilung Icancer.
1. Question 2
I I
• 0.125 Iout Iof I0.125 Ipoints
Many Iof Ithe Iresponses Ito Istress Iare Iattributed Ito Iactivation Iof Ithe Isympathetic Inervous
IsystemIand
Iare Imediated Iby
Selected IAnswer: b. Inorepinephrine.
CI orrect IAnswer: b. Inorepinephrine.
Response
Norepinephrine Iis Isecreted Iin Iresponse Ito Iactivation Iof Ithe Isympathetic
IFeedbac
Inervous sI ystem Iduring Istress Iby Ithe Iadrenal Imedulla. ICortisol Iis Isecreted
k
Iby Ithe Iadrenal cI ortex. IGlucagon Iis Isecreted Iby Ithe Ipancreas. IACTH Iis
:
Isecreted Iby Ithe Ipituitary gI land.
1. Question 3
I I
• 0.125 Iout Iof I0.125 Ipoints
The Inurse Iis Iswabbing Ia Ipatient’s Ithroat Ito Itest Ifor Istreptococcal Ipharyngitis. IThe Inurse
Imust Iunderstand Ithat Itests Isuch Ias Ithis Idiffer Iin Ithe Iprobability Ithat Ithey Iwill Ibe Ipositive
Ifor Ia Icondition Iwhen Iapplied Ito Ia Iperson Iwith Ithe Icondition; Ithis Iprobability Iis Itermed
Isensitivity.
Selected IAnswer: b.
,I True CI orrect IAnswer:
b. ITrue
Response The Isensitivity Iof Iany Itest Irefers Ito Ithe Iprobability Ithat Ithe Itest Iwill Ibe
Ipositive
, Feedback: when Iapplied Ito Ia Iperson Iwith Ithe Icondition Iand Iwill Inot Iprovide Ia
Ifalse Inegative Iresult. IIn Icontrast, Ispecificity Iis Ithe Iprobability Ithat Ia
Itest Iwill Ibe Inegative Iwhen Iapplied Ito Ia Iperson Iwho Idoes Inot Ihave Ia
Igiven Icondition.
1. Question 4
I I
• 0.125 Iout Iof I0.125 Ipoints
All Ithese Icellular Iresponses Iare Ipotentially Ireversible Iexcept
Selected IAnswer: b. Inecrosis.
CI orrect IAnswer: b. Inecrosis.
Response
IFeedbac
Necrosis Irefers Ito Ideath Iof Icells/tissue Iand Iis Inot Ireversible. IMetaplasia
Irefers Ito tI he Ireplacement Iof Ione Idifferentiated Icell Itype Iwith Ianother Ifrom
k
Ipersistent Iinjury Iand Iis Ireversible Iwhen Ithe Iinjury Istops. IAtrophy Ioccurs
:
Ibecause Iof Ilack Iof Iuse Iof Ian Iorgan Iand Iis Ireversible. IHyperplasia Iis Ian
Iincrease Iin Ithe Inumber Iof Icells Ifrom Iincreased Iphysiologic Idemands Ior
Ihormonal Istimulation Iand Iis Ireversible.
1. Question 5
I I
• 0.125 Iout Iof I0.125 Ipoints
Coagulative Inecrosis Iis Icaused
I by
Selected IAnswer: a. Iinterrupted Iblood Isupply.
CI orrect IAnswer: a. Iinterrupted Iblood Isupply.
Response
IFeedbac
Coagulative Inecrosis Iresults Ifrom Iinterrupted Iblood Isupply Ileading Ito
Iischemic cI ell Iinjury. ILiquefactive Inecrosis Iresults Ifrom Idissolving Iof Idead
k
Icells Iand Icyst Iformation. IFat Inecrosis Iis Icaused Iby Itrauma Ior Ipancreatitis.
:
ICaseous Inecrosis Iis Icaused Iby Ilung Itissue Idamage Isuch Ias Ithat Icaused Iby
Ituberculosis.
1. Question 6
I I
• 0.125 Iout Iof I0.125 Ipoints
The Imost Icommon Itumor-suppressor Igene Idefect Iidentified Iin Icancer Icells Iis
SI elected IAnswer: c. IP53.
Correct IAnswer: c. IP53.
Response k
IFeedbac :
