Final (elaborations) Internal 2 (INT2)

Endocrinology 2023

Anki:
https://docs.google.com/document/d/e/2PACX-1vSQn2wJh9LLddtO9kNOG
w2aOy0PmT3ZCXJRdAsOEw17JNofV_aBXZoapVpUtynccr2jIt9n7ANIQDv
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● Hyperprolactinemia is not an adverse event related to the treatment with:
● A. Bisphosphonates
● b.MAO inhibitors
● c.Dopamine-receptor antagonists (metoclopramide)
● d.Neuroleptics
● e.Contraceptives
○ c.Dopamine-receptor antagonists (metoclopramide)


● Side effects of corticosteroid therapy are #19
● A. Deterioration or initiation of diabetes mellitus
● B. Increased susceptibility to infections
● C. Osteoporosis
● D. Aseptic necrosis of the femoral neck
● E. All listed
○ E. All listed



● Which of the following is not a cause for primary hypocorticism?
● a. Autoimmune adrenalitis;
● b. Congenital adrenal aplasia;
● c. Adrenal sarcoidosis;
● d. Craniopharyngioma;
● e. Meningoccocal sepsis (Waterhouse-Friderichsen syndrome).
○ d. Craniopharyngioma;


● A patient with acromegaly, hypothyroidism and hypocorticism could also have:
● a. Hypergonadotropic hypogonadism;
● b. Hypogonadotropic hypogonadism;
● c. Hypogonadotropic hypergonadism;
● d. Hypergonadotropic hypergonadism;
● e. None of the above.
○ b. Hypogonadotropic hypogonadism;

,● After a successful surgical removal of cortisol secreting adenoma there is a risk
of:
● a. Postoperative hypercorticism;
● b. Postoperative hypocorticism;
● c. Postoperative hypothyroidism;
● d. Postoperative hypopituitarism;
● e. There is no risk of postoperative hormonal dysfunction ;
○ b. Postoperative hypocorticism;

● Hirsutism is:
● a. Excessive body hair in men;
● b. Excessive body hair of male-pattern in women;
● c. Excessive body hair in men and women;
● d. Reduced body hair in men;
● e. Reduced body hair in women.
○ b. Excessive body hair of male-pattern in women;

● In Turner syndrome there is:
● a. Hypogonadotropic hypogonadism;
● b. Hypergonadotropic hypogonadism;
● c. Hypergonadotropic hypergonadism;
● d. Hypogonadotropic hypergonadism;
● e. Testicle dysfunction;
○ b. Hypergonadotropic hypogonadism;

● In polycystic ovary syndrome the LH/FSH ratio is:
● a. Decreased;
● b. Increased;
● c. Remains unchanged;
● d. Highly decreased;
● e. Depends on the time of the measurement.
○ b. Increased;

● Women with polycystic ovary syndrome have a higher risk of:
● a. Hyperthyroidism;
● b. Toxic adenoma;
● c. Graves’ disease;
● d. Cardio-vascular disease;
● e. All of the above.
○ d. Cardio-vascular disease;

● Women with polycystic ovary syndrome have a higher risk of:
● a. Toxic adenoma;

,● b. Hypocorticism;
● c. Diabetes mellitus type 2;
● d. Hypopituitarism;
● e. All of the above.
○ c. Diabetes mellitus type 2;

● Women with polycystic ovary syndrome have a higher risk of:
● a. Toxic adenoma;
● b. Hypocorticism;
● c. Hypopituitarism;
● d. Gestational diabetes;
● e. All of the above.
○ d. Gestational diabetes;

● Women with polycystic ovary syndrome have a higher risk of:
● a. Toxic adenoma;
● b. Carbohydrate metabolism disorders;
● c. Hypocorticism;
● d. Hypopituitarism;
● e. All of the above.
○ b. Carbohydrate metabolism disorders;

● Women with polycystic ovary syndrome have a higher risk of:
● a. Toxic adenoma;
● b. Hypocorticism;
● c. Infertility;
● d. Hypopituitarism;
● e. All of the above.
○ c. Infertility;

● The primary cause of the pathogenesis of polycystic ovary syndrome is:
● a. Increased insulin sensitivity;
● b. Insulin resistance;
● c. Decreased insulin levels;
● d. All of the above;
● e. None of the above.
○ b. Insulin resistance;

● A common clinical feature of the polycystic ovary syndrome is:
● a. Hirsutism;
● b. Acne;
● c. Irregular menstrual cycle;
● d. All of the above;
● e. None of the above.

, ○ d. All of the above;

● Which of the following is ovarian hyperandrogenism?
● a. Addison’s disease;
● b. Androgen-secreting adrenal adenoma;
● c. Polycystic ovary syndrome;
● d. Primary hyperaldosteronism;
● e. None of the above.
○ c. Polycystic ovary syndrome;

● For polycystic ovary syndrome is not typical:
● a. Visceral obesity;
● b. Hyperandrogenism;
● c. Hypotonia;
● d. Hyperinsulinemia;
● e. None of the above.
○ c. Hypotonia;

● Which medication can be used for the treatment of polycystic ovary syndrome?
● a. Gliclaside;
● b. Metformin;
● c. Glimepiride;
● d. Glibenclamide;
● e. Glipizide
○ b. Metformin;

● Hyperinsulinemia results in:
○ Decreased uric acid clearance - hyperuricemia

● Which conditions can be presented with pseudo-Cushing’s syndrome?
● a. Chronic alcoholism;
● b. Depression;
● c. Pregnancy;
● d. Chronic alcoholism, depression and obesity;
● e. Depression, chronic glucocorticoid treatment.
○ d. Chronic alcoholism, depression and obesity;

● Primary hyperaldosteronism is:
● a. autonomic aldosterone secretion from the adrenal gland/glands;
● b. Excessive aldosterone secretion caused by increased activation of the
renin-angiotensin system;
● c. Both a. and b.;
● d. Excessive secretion of cortisol;
● e. None of the above.