Chapter 12 Talaros Foundations in Microbiology Quiz Test Bank Complete Solution 2023

Chapter 12. Talaros Foundations in Microbiology Quiz Test Bank Complete Solution 2023 Common metabolic products of aerobic bacteria and fungi is known as what? correct answers Antibiotics By inhibiting the other microbes in the same habitat, antibiotic producers have less competition for _____ and ____ correct answers nutrients, space Drugs should kill or inhibit microbial cells without simultaneously damaging host tissues. This process is known as what? correct answers Selectively toxic _____ is effective on a small range of microbes correct answers Narrow-spectrum ____ has the greatest range of activity correct answers Broad-spectrum _________ and __________ block synthesis of peptidoglycan, causing the cell wall to lyse correct answers Penicillin, cephalosporin What interacts with phospholipids and cause leakage, particularly in gram-negative bacteria? correct answers Polymyxins ________ and ________ form complexes with sterols on fungal membranes which causes leakage correct answers Amphotericin B, nystatin Antiviral drugs that insert in viral nucleic acid, preventing replication are _____ of purines and pyrimidines? correct answers analogs _______ binds and cross-links the double helix;_______ inhibit DNA helicases correct answers Chloroquine, quinolones (streptomycin, gentamycin) insert on sites on the 30S subunit and cause misreading of mRNA. This process is known as what? correct answers Aminoglycosides Blocked attachment of tRNA on the A acceptor site and stop further synthesis is known as what? correct answers Tetracyclines _______ and _______ block enzymes required for tetrahydrofolate synthesis needed for DNA and RNA synthesis correct answers Sulfonamides, trimethoprim During _______ the drug competes with normal substrate for enzyme's active site correct answers