Toxoplasma gondii
Dr J Mudenda
, Lecture outline
• INTRODUCTION
• EPIDEMIOLOGY
• LIFE CYCLE
• PATHOGENICITY AND VIRULENCE FACTORS
• CLINICAL PRESENTATION AND TREATMENT
• CONCLUSION AND RECOMMENDATION
• REFERENCES
, Introduction
• T. gondii was first discovered in 1908 in Tunis within the tissue of a
North African rodent,Ctenodactylus gondii .
• In the same year it was also described in Brazil in rabbits by Nicolle
and Manceaux.
• It was rediscovered in 1935 in the brain of guinea pigs
• In 1939 it was found as the cause of encephalitis in 31 day old infa
, • In 1969 infective cysts were detected in the stools of cats.
• A member of the Apicomplexa related to plasmodium,isospora and
others.
• It is a single celled intracellular protozoan that causes Toxoplasmos
parasitic disease.
• Found in several animals including cattle,pigs,sheep,also birds and
humans but the essential reservoir host is the common house cat a
other felines.
Dr J Mudenda
, Lecture outline
• INTRODUCTION
• EPIDEMIOLOGY
• LIFE CYCLE
• PATHOGENICITY AND VIRULENCE FACTORS
• CLINICAL PRESENTATION AND TREATMENT
• CONCLUSION AND RECOMMENDATION
• REFERENCES
, Introduction
• T. gondii was first discovered in 1908 in Tunis within the tissue of a
North African rodent,Ctenodactylus gondii .
• In the same year it was also described in Brazil in rabbits by Nicolle
and Manceaux.
• It was rediscovered in 1935 in the brain of guinea pigs
• In 1939 it was found as the cause of encephalitis in 31 day old infa
, • In 1969 infective cysts were detected in the stools of cats.
• A member of the Apicomplexa related to plasmodium,isospora and
others.
• It is a single celled intracellular protozoan that causes Toxoplasmos
parasitic disease.
• Found in several animals including cattle,pigs,sheep,also birds and
humans but the essential reservoir host is the common house cat a
other felines.