Molecular Diagnostics Chapter 7(All Correct Answers Avaible).

Molecular Diagnostics Chapter 7(All Correct Answers Avaible)chromosome mutation - ANSWERS.change in chromosome structure Genome mutations - ANSWERS.changes in chromosome number Euploid - ANSWERS.an individual with How many base pairs are in the human genome? - ANSWERS.2.9 billion What is the difference between a mutation and a polymorphism? - ANSWERS.mutations are reserved for rare changes in DNA like those found in cancer. Polymorphisms are variants that occur in 1-2% of the population and do not affect phenotype heavily What are the three largest and smallest chromosomes? - ANSWERS.largest: 1, 2 3 smallest: 22, Y, 19 What is an example of a balanced polymorphism? - ANSWERS.sickle cell anemia What is an example of a benign polymorphism? - ANSWERS.Blood Type ABO, HLA-type gene mutation - ANSWERS.a change in the base sequence of a gene the appropriate number of chromosomes for their species Aneuploid - ANSWERS.an individual with an error in chromosome number; includes deletions and duplications of chromosome segments Chromosome behavior is dependent on chromosome _________________ and DNA _______________ - ANSWERS.structure and sequence position effect - ANSWERS.dependence of the expression of a gene on the gene's location in the genome Compaction - ANSWERS.winding of DNA into metaphase chromosomes Histones - ANSWERS.Globular protein that assist in DNA packaging in eukaryotes. Histones form octamers around which DNA is wound to form a nucleosome. (H2a, H2b, H3, H4) X2 .