TEST BANK FOR
BIOCHEMISTRY,
5TH EDITION
REGINALD H.
GARRETT,
CHARLES M.
GRISHAM
,Mathews, van Holde, Appling, and Anthony-Cahill, Biochemistry
Chapter 2: The Matrix of Life: Weak Interactions in an Aqueous Environment
Multiple Choice Questions
1) Which of the following represents the breaking of a noncovalent interaction?
A) hydrolysis of an ester
B) dissolving of salt crystals
C) ionization of water
D) decomposition of hydrogen peroxide
E) none of the above
Answer: B
Difficulty: 1 Topic: The Nature of Noncovalent Interactions
2) Which of the following is the most likely noncovalent interaction observed between a
carboxylic acid and an alcohol?
A) charge-charge interaction
B) charge-dipole interaction
C) dipole-dipole interaction
D) dipole-induced dipole interaction
E) formation of an ester bond
Answer: B
Difficulty: 1 Topic: The Nature of Noncovalent Interactions
3) Which of the following atoms could interact through a hydrogen bond?
A) the oxygen of a ketone and the hydrogen of an aldehyde
B) the oxygen of methanol and a hydrogen on the methyl carbon of methanol
C) the hydrogen of an amine and the oxygen of an alcohol
D) the hydrogen on an aromatic ring and the oxygen of carbon dioxide
E) none of the above
Answer: C
Difficulty: 2 Topic: The Nature of Noncovalent Interactions
1
, Mathews, van Holde, Appling, and Anthony-Cahill, Biochemistry
Chapter 2: The Matrix of Life: Weak Interactions in an Aqueous Environment
4) Which of the following would likely form micelles in an aqueous solution?
A) hexane
B) glucose
C) glutamic acid
D) dodecanoic acid
E) none of the above
Answer: D
Difficulty: 2 Topic: The Role of Water in Biological Processes
5) Which of the following best explains the hydrogen bonding that occurs in water?
A) the average number of H-bonds formed by one water molecule is the same in liquid and
solid water, the only difference is the duration of the H-bond
B) the number of H-bonds formed by one water molecule is greater in liquid water than in
solid water
C) the structure of liquid water is best described as flickering clusters of H-bonds due to the
relative short duration of individual H-bonds
D) each water molecule is capable of forming 8 H-bonds: 2 from each lone pair of electrons
and 2 from each hydrogen
E) none of the above
Answer: C
Difficulty: 2 Topic: The Role of Water in Biological Processes
6) Given the structure of a glucose molecule, which of the following explains the hydrogen
bonding between glucose and water?
A) H-bonds will form with glucose always being the H-bond donor
B) H-bonds will form with water always being the H-bond donor
C) each glucose molecule could H-bond with as many as 17 water molecules
D) due to the cyclic structure of glucose, H-bonding with water does not occur
E) none of the above
Answer: C
Difficulty: 2 Topic: The Role of Water in Biological Processes
2
BIOCHEMISTRY,
5TH EDITION
REGINALD H.
GARRETT,
CHARLES M.
GRISHAM
,Mathews, van Holde, Appling, and Anthony-Cahill, Biochemistry
Chapter 2: The Matrix of Life: Weak Interactions in an Aqueous Environment
Multiple Choice Questions
1) Which of the following represents the breaking of a noncovalent interaction?
A) hydrolysis of an ester
B) dissolving of salt crystals
C) ionization of water
D) decomposition of hydrogen peroxide
E) none of the above
Answer: B
Difficulty: 1 Topic: The Nature of Noncovalent Interactions
2) Which of the following is the most likely noncovalent interaction observed between a
carboxylic acid and an alcohol?
A) charge-charge interaction
B) charge-dipole interaction
C) dipole-dipole interaction
D) dipole-induced dipole interaction
E) formation of an ester bond
Answer: B
Difficulty: 1 Topic: The Nature of Noncovalent Interactions
3) Which of the following atoms could interact through a hydrogen bond?
A) the oxygen of a ketone and the hydrogen of an aldehyde
B) the oxygen of methanol and a hydrogen on the methyl carbon of methanol
C) the hydrogen of an amine and the oxygen of an alcohol
D) the hydrogen on an aromatic ring and the oxygen of carbon dioxide
E) none of the above
Answer: C
Difficulty: 2 Topic: The Nature of Noncovalent Interactions
1
, Mathews, van Holde, Appling, and Anthony-Cahill, Biochemistry
Chapter 2: The Matrix of Life: Weak Interactions in an Aqueous Environment
4) Which of the following would likely form micelles in an aqueous solution?
A) hexane
B) glucose
C) glutamic acid
D) dodecanoic acid
E) none of the above
Answer: D
Difficulty: 2 Topic: The Role of Water in Biological Processes
5) Which of the following best explains the hydrogen bonding that occurs in water?
A) the average number of H-bonds formed by one water molecule is the same in liquid and
solid water, the only difference is the duration of the H-bond
B) the number of H-bonds formed by one water molecule is greater in liquid water than in
solid water
C) the structure of liquid water is best described as flickering clusters of H-bonds due to the
relative short duration of individual H-bonds
D) each water molecule is capable of forming 8 H-bonds: 2 from each lone pair of electrons
and 2 from each hydrogen
E) none of the above
Answer: C
Difficulty: 2 Topic: The Role of Water in Biological Processes
6) Given the structure of a glucose molecule, which of the following explains the hydrogen
bonding between glucose and water?
A) H-bonds will form with glucose always being the H-bond donor
B) H-bonds will form with water always being the H-bond donor
C) each glucose molecule could H-bond with as many as 17 water molecules
D) due to the cyclic structure of glucose, H-bonding with water does not occur
E) none of the above
Answer: C
Difficulty: 2 Topic: The Role of Water in Biological Processes
2
