NR566 -Week 5 Study Guide Questions and Answers Already Graded A

Regarding osteoporosis, what are the two SERM drugs? Ans-Tamoxifen -Raloxifene Tamoxifen is a good drug because it protects against osteoporosis, but what is it's downside? Ans-Higher risk for cancer -Higher risk for blood clots What is the the awesome benefit of Tamoxifen other than bone health? Ans- Promotes good blood lipid levels What is one thing that makes Raloxifene better than Tamoxifen? Ans-Lower risk for cancer What is the only drug approved for prevention and treatment of osteoporosis? Ans-Duavee (conjugated estrogens/bazedoxifene) What drug prevents osteoporosis and vasomotor symptoms in postmenopausal women with a uterus? Ans-Duavee (conjugated estrogens/bazedoxifene) What are the 3 main benefits of hormone therapy? Ans-suppression of vasomotor symptoms -prevention of urogenital atrophy -prevention of osteoporosis and related fractures Does urogenital atrophy and osteoporosis prevention sustain after withdrawal of HT? Ans--No, benefits will decline after HT withdrawal Although HT therapy is great for bone loss prevention, what will happen when HT is stopped? Ans-bone mass rapidly decreases by approximately 12% ---Therapy must be life long-- Examples of progestins Ans-Medroxyprogesterone acetate -Norethindrone A patient has undiagnosed vaginal bleeding, should she be prescribed HT? Ans- No, don't give HT with undiagnosed vaginal bleeding Julie has some blood clotting issues in his body. He has active thrombophlebitis & thromboembolic disorders Should she use HT? Ans-No, better not use HT with blood and clotting issues.