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Class Notes: Neurotransmitters and its types

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Comprehensible and easy notes of neurotransmitters and its types. Easy to understand so that the concepts are grasped. pretty useful for medical students.

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Neurotransmitters and its types.

Neurotransmitters
 Neurotransmitters are chemical messengers. They are produced in the Basal
Ganglia (basal ganglia is formed by 5 to 7 nuclei).
 The main job of neurotransmitters is to carry the chemical signals from one neuron
cell to the next target cell i.e., nerve cell, muscle cell or gland.
 Neurotransmitters are of 3 types in nature. They are excitatory, inhibitory and
dual.
Excitatory: Responsible for exciting their target neurons. Excitatory Neurons in the
brain are often glutamatergic.
Inhibitory: responsible for reducing the excitation such as while sleeping or they are
responsible for inhibiting their target neurons. These include neurotransmitters such
as dopamine, acetylcholine, Serotonin.
Dual: performing both Excitatory and Inhibitory Functions.


Acetylcholine
 Secreted by the basal ganglia
 Present in a humungous amount
 Depends on the Secretory Vesicles. (Acetylcholine is released about 10,000 in
number when secretory vesicle is ruptured).
 Acetylcholine is released by the Motor Cortex
 It is dual in nature
 It is transported by Vagus Nerve i.e., Largest Nerve.
 Performs Bronchoconstriction in the Lungs.
 Responsible for controlling overall stomach motility.


Dopamine (Inhibitory in Nature)
 Produced by Basal ganglia
 The critical brain region that is responsible for the production of dopamine is
Substantia Niagara.
 It is responsible for controlling fine motor skills
 It is responsible for the sensations of reward, pleasure, euphoria
Parkinson’s Disease
At a certain age after 70 years the Substantia Niagara decorates thus dopamine is
not produced, this is known as Parkinson’s Disease.

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Uploaded on
June 24, 2023
Number of pages
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Written in
2022/2023
Type
Class notes
Professor(s)
Dr. swaira
Contains
Physiology class

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