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Lecture notes of pharmacy

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Its all about the different types pf subjects and topics related to them. Each having short notes. Which can be study easily. Its already in capsule form. Its mainly includes nsaids, cancer drugs, bloodproducts, performance evaluation etc..

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Institution
Kerala University Of Health Science
Course
BP302T

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QUANTITATIVE STRUCTURE ACTIVITY
RELATIONSHIPS (QSAR)-LIPOPHILIC
PARAMETER



By
Mrs.Meena Chandran
Asst.Professor
Dept.Pharm.Chemistry
SJCOPS

, HYDROPHOBICITY/LIPOPHILICITY

Hydrophobic character of a drug is crucial to how easily it
crosses the cell membrane and may also important in receptor
interactions.
Hydrophobicity of a drug is measured experimentally by testing the
drugs relative distribution in octanol water mixture. This relative
distribution is known as PARTITION COEFFICIENT.

Partition Coefficient P = [conc. Drug in in octanol]
[Conc.of drug in water]
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Institution
Kerala University Of Health Science
Course
BP302T
All documents for this subject (20)

Document information

Uploaded on
June 25, 2023
Number of pages
13
Written in
2019/2020
Type
Class notes
Professor(s)
Harikumar
Contains
All classes

Subjects

  • pharmacy
  • medicinalchemistry
  • chemistry
  • lecturenotes
  • examnotes
  • qsar
  • parenteral
  • bloodproduct
  • performance
  • nsaids
  • cancer
  • sutures
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