ASCP MLS EXAM QUESTIONS & ANSWERS 2023 ( A+
GRADED 100% VERIFIED)
What feature is most often found with patients with a splenectomy on a Wright's
stained blood smear?
Howell-Jolly bodies
Patients with antibody to the following antigen are immune to Hepatitis B:
Surface antigen (HbSAg)
Which two of the following tests are helpful for documenting previous
Streptococcal throat and skin infections:
ASO titer and Anti-DNase B
In mass spectrometry, the "appearance potential" is defined as the:
Minimum energy required for the appearance of a particular fragment ion in mass
spectrum
What is generally accepted as the lower threshold value for semen pH from fertile
males?
7.2
Coulometry:
An automated method for measuring chloride which generates silver ions in the reaction
Erythroleukemia:
Also known as Acute Myelogenous Leukemia type M6. This type is associated with
either the presence of both erythroid and myeloid precursors OR strictly erythroid
precursors.
Myelomonocytic leukemia
Is associated with an increase in myeloid and monocytic cell precursors, but not red
blood cell precursors
Species that are Lysine (+), arginine (=) and ornithine (+):
Enterobacter aerogenes, Edwardsiella species and most Serratia species
Lysine reaction for all Citrobacter:
Negative
Key identifying characteristic for Pantoa (Enterobacter) agglomerans:
negative reactions for the three decarboxylases commonly tested ( Lysine, arginine and
ornithine)
Which organism is MOST likely responsible for septic reactions associated with
Red Blood Cell transfusions?
Yersina entercolitica is most likely responsible for septic reactions in transfusions of Red
Blood Cells. This organism is usually acquired by ingestion of contaminated food and
causes mild symptoms of abdominal pain and diarrhea. Growth of Y. entercolitica is
enhanced in iron-rich environments such as red cell components.
Gaucher's disease
The most common lysosomal storage disease caused by insufficient activity of the
lysosomal enzyme glucocerebrosidase that leads to the deposition of glucocerebroside
in cells of the macrophage-monocyte system.
Diseases associated with dysfunctions of polymorphonuclear neutrophils (PMNs)
, Chediak-Higashi syndrome (CH), Chronic granulomatous disease (CGD),
Myeloperoxidase deficiency (MPO)
Nephrotic Syndrome:
Caused by damage to the kidneys, especially the basement membrane of the
glomerulus; which causes abnormal excretion of protein and red blood cells in the urine.
Fats are also present in the urine in most cases. A foamy appearance of the urine is a
key characteristic of this condition.
Clinical symptoms include:
Swelling
Weight gain from fluid retention
Poor appetite
High blood pressure
Key Biochemical reactions for Enterobacteriaceae:
The key biochemical reactions by which the family Enterobacteriaceae can be identified
include fermentation of carbohydrates, reduction of nitrates to nitrites and the absence
of cytochrome oxidase activity.
ANA
See 2 quiz #27
Prozone effect:
Results in a false positive reaction; is the result of antibody excess and dilution of
antibody can help prevent its occurrence
Purpose of a bi-chromatic analyzer with dual wavelengths is:
Minimize the effect of interference
Key characteristics of Micrococcus:
Susceptible to bacitracin ("A") and resistant to furazolidone; gram positive cocci in
tetras, bacteria cells of micrococcus luteus are larger than those of the staphylococci
and can arrange in tetras
What is the glomerular filtration rate for a patient with a serum creatinine of 2
mg/dL, if the urine creatinine was 124 mg/dL and the urine volume was 2.2 L/24
hrs?
95 mL/min
One method of calculating a glomerular filtration rate is using creatinine and urine
volume to determine creatinine clearance. The equation is as follows:
Creatinine Clearance = (urine creatinine X urine flow rate) / plasma creatinine; where
urine flow rate = volume in mL /24 hours x h/60 min)
In this case = creatinine clearance = 124 X (2200/24 x hour/60) / 2 = 94.7 or 95 ml/min
Estrogen and progesterone markers are most commonly used to provide
prognostic information about:
Breast cancer
The prozone effect ( when performing a screening titer) is most likely to result in:
Prozone effect (due to antibody excess) will result in an initial false negative in spite of
the large amount of antibody in the serum, followed by a positive result as the specimen
is diluted.
GRADED 100% VERIFIED)
What feature is most often found with patients with a splenectomy on a Wright's
stained blood smear?
Howell-Jolly bodies
Patients with antibody to the following antigen are immune to Hepatitis B:
Surface antigen (HbSAg)
Which two of the following tests are helpful for documenting previous
Streptococcal throat and skin infections:
ASO titer and Anti-DNase B
In mass spectrometry, the "appearance potential" is defined as the:
Minimum energy required for the appearance of a particular fragment ion in mass
spectrum
What is generally accepted as the lower threshold value for semen pH from fertile
males?
7.2
Coulometry:
An automated method for measuring chloride which generates silver ions in the reaction
Erythroleukemia:
Also known as Acute Myelogenous Leukemia type M6. This type is associated with
either the presence of both erythroid and myeloid precursors OR strictly erythroid
precursors.
Myelomonocytic leukemia
Is associated with an increase in myeloid and monocytic cell precursors, but not red
blood cell precursors
Species that are Lysine (+), arginine (=) and ornithine (+):
Enterobacter aerogenes, Edwardsiella species and most Serratia species
Lysine reaction for all Citrobacter:
Negative
Key identifying characteristic for Pantoa (Enterobacter) agglomerans:
negative reactions for the three decarboxylases commonly tested ( Lysine, arginine and
ornithine)
Which organism is MOST likely responsible for septic reactions associated with
Red Blood Cell transfusions?
Yersina entercolitica is most likely responsible for septic reactions in transfusions of Red
Blood Cells. This organism is usually acquired by ingestion of contaminated food and
causes mild symptoms of abdominal pain and diarrhea. Growth of Y. entercolitica is
enhanced in iron-rich environments such as red cell components.
Gaucher's disease
The most common lysosomal storage disease caused by insufficient activity of the
lysosomal enzyme glucocerebrosidase that leads to the deposition of glucocerebroside
in cells of the macrophage-monocyte system.
Diseases associated with dysfunctions of polymorphonuclear neutrophils (PMNs)
, Chediak-Higashi syndrome (CH), Chronic granulomatous disease (CGD),
Myeloperoxidase deficiency (MPO)
Nephrotic Syndrome:
Caused by damage to the kidneys, especially the basement membrane of the
glomerulus; which causes abnormal excretion of protein and red blood cells in the urine.
Fats are also present in the urine in most cases. A foamy appearance of the urine is a
key characteristic of this condition.
Clinical symptoms include:
Swelling
Weight gain from fluid retention
Poor appetite
High blood pressure
Key Biochemical reactions for Enterobacteriaceae:
The key biochemical reactions by which the family Enterobacteriaceae can be identified
include fermentation of carbohydrates, reduction of nitrates to nitrites and the absence
of cytochrome oxidase activity.
ANA
See 2 quiz #27
Prozone effect:
Results in a false positive reaction; is the result of antibody excess and dilution of
antibody can help prevent its occurrence
Purpose of a bi-chromatic analyzer with dual wavelengths is:
Minimize the effect of interference
Key characteristics of Micrococcus:
Susceptible to bacitracin ("A") and resistant to furazolidone; gram positive cocci in
tetras, bacteria cells of micrococcus luteus are larger than those of the staphylococci
and can arrange in tetras
What is the glomerular filtration rate for a patient with a serum creatinine of 2
mg/dL, if the urine creatinine was 124 mg/dL and the urine volume was 2.2 L/24
hrs?
95 mL/min
One method of calculating a glomerular filtration rate is using creatinine and urine
volume to determine creatinine clearance. The equation is as follows:
Creatinine Clearance = (urine creatinine X urine flow rate) / plasma creatinine; where
urine flow rate = volume in mL /24 hours x h/60 min)
In this case = creatinine clearance = 124 X (2200/24 x hour/60) / 2 = 94.7 or 95 ml/min
Estrogen and progesterone markers are most commonly used to provide
prognostic information about:
Breast cancer
The prozone effect ( when performing a screening titer) is most likely to result in:
Prozone effect (due to antibody excess) will result in an initial false negative in spite of
the large amount of antibody in the serum, followed by a positive result as the specimen
is diluted.
