MLS ASCP Exam 2023, Complete
Verified Solution 100%
Procainamide
-Answer: NAPA
-p. 86-Ant antiarrhythmic drug that has a metabolite with the same drug action
-Procainamide is metabolized to N-Acetylprocainamide (NAPA)
- Must quantify both. Although they have the same drug affect, difference in half- life
may cause NAPA to accumulate in the blood and produce toxic affects even at
therapeutic levels of procainamide.
loose clusters of small spherical microconidia, positive urease
-Answer: Trichophyton mentagrophytes -Trichophyton is the only Dermatophyte with
two colony types : macroconidia and microconidia. - T. mentagrophytes
characteristically produce "grapelike clusters" of microconidia. - Positive in the hair
perforation test.
Beta -HCG tumor marker
Answer: chorocarcinoma
-The are are 2 forms of hCG Alpha (common form) and Beta (unique form)
5HIAA 5-hydroxyindoleacetic acid
-Answer: carcinoid tumors -5HIAA: primary metabolite of serotonin, a chemical
substance (neurotransmitter) that transmits messages between nerve cells. -Large
quantities of serotonin and 5-HIAA may be produced by some carcinoid tumors.-
Carcinoid tumors are slow-growing noncancerous or cancerous neuroendocrine masses
that can form in the GI tract, especially in the appendix, and in the lungs.
Proteus vulgaris vs P. mirabilis indole test
P. vulgaris is indole pos. P. mirabilis is indole neg
Hydatid cyst fluid
used to neutralize Anti-P1 antibody
Antacid overdose
Check pH
Prolonged PT, PTT, and thrombin after collecting from catheter
heparin contamination
mixing study that was performed with a prolonged PTT that couldn't be corrected
DRVVT (Dilute Russell Viper Venom Test)
two pt's ran in duplicate (PT and PTT). The PTT seemed to always be prolonged
but PT looked ok
check the CaCl/phospholipid reagent delivery
Patient is on coumadin therapy, what will be affected
Decreased protein C
Lot's of stomatocytes
Liver disease
Burr cells
Uremia
, Picture of target cells with hemoglobin C crystals. The white count was high on
instrument 1, so a second instrument was used with a stronger lysing agent, and
the white count was corrected
anti-lysing target cells are what increased the white count? Erythrocytes containing
hemoglobin C do not lyse normally (sickle cell diseases)
A sodium citrate tube was drawn for a HCT on a pt but the hematocrit was
abnormal
recollect with decreased anticoagulant. high hct (>55%) causes low plasma so you need
less anticoagulant
Question that gives a red blood cells count, HGB, and HCT. I did the rule of 3 and
found that the HGB didn't meet the rule of 3 because it was too high
check for lipemia (elevates HGB)
PBS with an elevated reticulocyte count and howell jolly bodies in the RBC's
-Answer: howell jolly bodies= DNA= Wright Stain
-Peppenheimer- Prussian blue stain
-which is not taken up by reticulocytes
-helpful in differentiating the two.
-Reticulocytes=Supravital/ new methylene blue stain
what is composed of DNA?
howell jolly bodies
-wright Stain
what falsely increases ESR
vibration, tilting of tube, higher temps, >1 hr test time, improper mixing of blood,
improper dilution
factors decreasing ESR
Polycythemia, Microcytosis (Hb C), Sickle cells, spherocytes, Anti-inflammatory
medications, Hypogammaglobulinemia, Hypofibrinogenemia (DIC), High WBC count,
Hyperviscosity
Factors increasing ESR
Anemia, Macrocytosis, Female gender, Age >50 years, Obesity, Pregnancy,
Hypercholesterolemia, cancer, multiple myeloma, rouleaux, infections, inflammation
what falsely decreases ESR
low blood/ room temps, air bubbles, tests <1 hr, improper mixing of blood, improper
dilution
lactic acid collection
separate from serum and put on ice
coefficient of variation
(standard deviation/ mean) X 100
Carbon dioxide electrode measures what
Used to measure free carbon dioxide ions by detecting pH. The change in pH is
measured by an internal pH sensor, which is proportional to the carbon dioxide level.
patient that had a random glucose >200 and an FPG >126. What do you do next?
diagnosis with diabetes mellitus.
(need secondary confirmation from 4 criteria. FRG >126, Random glucose >200, ogtt
>200, or Hb A1c >6.5)
Verified Solution 100%
Procainamide
-Answer: NAPA
-p. 86-Ant antiarrhythmic drug that has a metabolite with the same drug action
-Procainamide is metabolized to N-Acetylprocainamide (NAPA)
- Must quantify both. Although they have the same drug affect, difference in half- life
may cause NAPA to accumulate in the blood and produce toxic affects even at
therapeutic levels of procainamide.
loose clusters of small spherical microconidia, positive urease
-Answer: Trichophyton mentagrophytes -Trichophyton is the only Dermatophyte with
two colony types : macroconidia and microconidia. - T. mentagrophytes
characteristically produce "grapelike clusters" of microconidia. - Positive in the hair
perforation test.
Beta -HCG tumor marker
Answer: chorocarcinoma
-The are are 2 forms of hCG Alpha (common form) and Beta (unique form)
5HIAA 5-hydroxyindoleacetic acid
-Answer: carcinoid tumors -5HIAA: primary metabolite of serotonin, a chemical
substance (neurotransmitter) that transmits messages between nerve cells. -Large
quantities of serotonin and 5-HIAA may be produced by some carcinoid tumors.-
Carcinoid tumors are slow-growing noncancerous or cancerous neuroendocrine masses
that can form in the GI tract, especially in the appendix, and in the lungs.
Proteus vulgaris vs P. mirabilis indole test
P. vulgaris is indole pos. P. mirabilis is indole neg
Hydatid cyst fluid
used to neutralize Anti-P1 antibody
Antacid overdose
Check pH
Prolonged PT, PTT, and thrombin after collecting from catheter
heparin contamination
mixing study that was performed with a prolonged PTT that couldn't be corrected
DRVVT (Dilute Russell Viper Venom Test)
two pt's ran in duplicate (PT and PTT). The PTT seemed to always be prolonged
but PT looked ok
check the CaCl/phospholipid reagent delivery
Patient is on coumadin therapy, what will be affected
Decreased protein C
Lot's of stomatocytes
Liver disease
Burr cells
Uremia
, Picture of target cells with hemoglobin C crystals. The white count was high on
instrument 1, so a second instrument was used with a stronger lysing agent, and
the white count was corrected
anti-lysing target cells are what increased the white count? Erythrocytes containing
hemoglobin C do not lyse normally (sickle cell diseases)
A sodium citrate tube was drawn for a HCT on a pt but the hematocrit was
abnormal
recollect with decreased anticoagulant. high hct (>55%) causes low plasma so you need
less anticoagulant
Question that gives a red blood cells count, HGB, and HCT. I did the rule of 3 and
found that the HGB didn't meet the rule of 3 because it was too high
check for lipemia (elevates HGB)
PBS with an elevated reticulocyte count and howell jolly bodies in the RBC's
-Answer: howell jolly bodies= DNA= Wright Stain
-Peppenheimer- Prussian blue stain
-which is not taken up by reticulocytes
-helpful in differentiating the two.
-Reticulocytes=Supravital/ new methylene blue stain
what is composed of DNA?
howell jolly bodies
-wright Stain
what falsely increases ESR
vibration, tilting of tube, higher temps, >1 hr test time, improper mixing of blood,
improper dilution
factors decreasing ESR
Polycythemia, Microcytosis (Hb C), Sickle cells, spherocytes, Anti-inflammatory
medications, Hypogammaglobulinemia, Hypofibrinogenemia (DIC), High WBC count,
Hyperviscosity
Factors increasing ESR
Anemia, Macrocytosis, Female gender, Age >50 years, Obesity, Pregnancy,
Hypercholesterolemia, cancer, multiple myeloma, rouleaux, infections, inflammation
what falsely decreases ESR
low blood/ room temps, air bubbles, tests <1 hr, improper mixing of blood, improper
dilution
lactic acid collection
separate from serum and put on ice
coefficient of variation
(standard deviation/ mean) X 100
Carbon dioxide electrode measures what
Used to measure free carbon dioxide ions by detecting pH. The change in pH is
measured by an internal pH sensor, which is proportional to the carbon dioxide level.
patient that had a random glucose >200 and an FPG >126. What do you do next?
diagnosis with diabetes mellitus.
(need secondary confirmation from 4 criteria. FRG >126, Random glucose >200, ogtt
>200, or Hb A1c >6.5)
