MSN 277 EXAM 2 (All Modules Checked;
Includes MDS, Leukemia, and Lymphoma)
What are the integumentary clinical manifestations of anemia? - ANSWER - - pallor r/t
decreased Hgb & decreased blood flow
- jaundice r/t hemolysis of RBCs which leads to increased concentration of bilirubin
- pruritus r/t bile concentrations on skin
What are the cardiovascular clinical manifestations of anemia? - ANSWER - - palpitations
- tachycardia
- systolic murmur and bruits
- angina/MI
- HF
What are the GI clinical manifestations of anemia? - ANSWER - - anorexia
- hepatosplenamegaly
- glossitis
- mucositis
- abdominal distension
- beefy, red tongue
What are the pulmonary clinical manifestations of anemia? - ANSWER - - dyspnea
- tachypnea
- orthopnea
What are the neurologic clinical manifestations of anemia? - ANSWER - - confusion
- paralysis
- irritability
- headache
- impaired judgment
- vertigo
- depression
What are the general clinical manifestations of anemia? - ANSWER - - fatigue
- sensitivity to cold
- weight loss
, What are the musculoskeletal clinical manifestations of anemia? - ANSWER - bone pain r/t
bond marrow overworking to produce more cells
What are the s/s of iron-deficiency anemia? - ANSWER - - may be asymptomatic in early course
- pallow
- glossitis
- cheilitis
- headache
- pasthesias
- burning escalation of tongue
What diagnostic studies are used for iron-deficiency anemia? - ANSWER - - Labs: Hgb/Hct, CBC,
serum iron, TIBC, transferrin, ferritin, bilirubin, folate
- guaiac test: stool for occult
- endoscopy and colonoscopy to ID source of bleeding (upper or lower)
- bone marrow biopsy
What are some chronic diseases that may lead to anemia? - ANSWER - - chronic inflammation
- autoimmune
-infectious diseases
- HF
- malignancies
What are s/s of anemia caused by acute blood loss? - ANSWER - - tachycardia
- postural hypotension
- air hunger
- thready pulse
- cool, clammy skin
- shock, lactic acidosis, potential death
What is ITP? - ANSWER - Immune Thrombocytopenia Purpura
- most common
- abnormal destruction of circulating platelets bc antibodies on the outside are recognized as
foreign (decreased platelet formation)
- primarily an autoimmune disease
What is TTP? - ANSWER - Thrombotic Thrombocytopenia Purpura
Includes MDS, Leukemia, and Lymphoma)
What are the integumentary clinical manifestations of anemia? - ANSWER - - pallor r/t
decreased Hgb & decreased blood flow
- jaundice r/t hemolysis of RBCs which leads to increased concentration of bilirubin
- pruritus r/t bile concentrations on skin
What are the cardiovascular clinical manifestations of anemia? - ANSWER - - palpitations
- tachycardia
- systolic murmur and bruits
- angina/MI
- HF
What are the GI clinical manifestations of anemia? - ANSWER - - anorexia
- hepatosplenamegaly
- glossitis
- mucositis
- abdominal distension
- beefy, red tongue
What are the pulmonary clinical manifestations of anemia? - ANSWER - - dyspnea
- tachypnea
- orthopnea
What are the neurologic clinical manifestations of anemia? - ANSWER - - confusion
- paralysis
- irritability
- headache
- impaired judgment
- vertigo
- depression
What are the general clinical manifestations of anemia? - ANSWER - - fatigue
- sensitivity to cold
- weight loss
, What are the musculoskeletal clinical manifestations of anemia? - ANSWER - bone pain r/t
bond marrow overworking to produce more cells
What are the s/s of iron-deficiency anemia? - ANSWER - - may be asymptomatic in early course
- pallow
- glossitis
- cheilitis
- headache
- pasthesias
- burning escalation of tongue
What diagnostic studies are used for iron-deficiency anemia? - ANSWER - - Labs: Hgb/Hct, CBC,
serum iron, TIBC, transferrin, ferritin, bilirubin, folate
- guaiac test: stool for occult
- endoscopy and colonoscopy to ID source of bleeding (upper or lower)
- bone marrow biopsy
What are some chronic diseases that may lead to anemia? - ANSWER - - chronic inflammation
- autoimmune
-infectious diseases
- HF
- malignancies
What are s/s of anemia caused by acute blood loss? - ANSWER - - tachycardia
- postural hypotension
- air hunger
- thready pulse
- cool, clammy skin
- shock, lactic acidosis, potential death
What is ITP? - ANSWER - Immune Thrombocytopenia Purpura
- most common
- abnormal destruction of circulating platelets bc antibodies on the outside are recognized as
foreign (decreased platelet formation)
- primarily an autoimmune disease
What is TTP? - ANSWER - Thrombotic Thrombocytopenia Purpura
