lOMoAR cPSD| 22830792
lOMoAR cPSD| 22830792
TEST BANK FOR Tietz Fundamentals Ofclinical
ChemistryAND Molecular Diagnostics 7TH
Edition BY Burti
Psychiatric/Mental Health Nursing (Santa Fe College)
Smartprep Examinations
since 2010
[2010 1
, lOMoAR cPSD| 22830792
TEST BANK FOR TIETZ FUNDAMENTALS OFCLINICAL CHEMISTRY AND
MOLECULAR DIAGNOSTICS 7TH EDITION BYBURTIS
TABLE OF CONTENTS:
I. PRINCIPLES OF LABORATORY MEDICINE
1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
2. Selection and Analytical Evaluation of Methods — With Statistical
Techniques
3. Clinical Evaluation of Methods
4. Evidence-Based Laboratory Medicine
5. Establishment and Use of Reference Values
6. Specimen Collection, Processing, and Other Preanalytical Variables
7. Quality Management
II. ANALYTICAL TECHNIQUES AND INSTRUMENTATION
8. Principles of Basic Techniques and Laboratory Safety
9. Optical Techniques
10. Electrochemistry and Chemical Sensors
11. Electrophoresis
12.Chromatography
13.Mass Spectrometry
14.Enzyme and Rate Analyses
15.Immunochemical Techniques 16
Automation
17. Point-of-Care Instrumentation
III. ANALYTES
18. Amino Acids, Peptides, and Proteins
19. Serum Enzymes
20. Tumor Markers and Cancer Genes
21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
22. Carbohydrates
23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Fac- tors
24. Electrolytes and Blood Gases
25. Hormones
26. Catecholamines and Serotonin
27. Vitamins, Trace Elements, Nutritional Assessment
28. Hemoglobin, Iron, and Bilirubin
29. Porphyrins and Porphyrias
30. Therapeutic Drugs and Their Management
[2010 2
, lOMoAR cPSD| 22830792
31. Clinical Toxicology
32. Toxic Metals
IV. PATHOPHYSIOLOGY
33. Diabetes
34. Cardiovascular Disease
35. Kidney Disease
36. Physiology and Disorders of Water, Electrolyte, and Acid-Base
Metabolism
37. Liver Disease
38. Gastrointestinal and Pancreatic Diseases
39. Disorders of Bone and Mineral Metabolism
40. Disorders of the Pituitary Gland
41. Disorders of the Adrenal Cortex
42. Thyroid Disorders
43. Reproduction-Related Disorders
44. Pregnancy and Prenatal Testing
45. Newborn Screening and Inborn Errors of Metabolism
46. Pharmacogenetics
V. MOLECULAR DIAGNOSTICS NEW!
47. Principles of Molecular Biology
48. Nucleic Acid Techniques and Applications
49. Genomes and Nucleic Acid Alterations
VI. REFERENCE INFORMATION
50. Reference Information for the Clinical Laboratory
[2010 3
, lOMoAR cPSD| 22830792
Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory
Medicine Test Bank
MULTIPLE
CHOICE
1. An individual working in a clinical chemistry laboratory is married to a sales
representative who works for a company that sells chemistry laboratory
supplies. When the laboratory manager requests a list of needed supplies, cost
of supplies, and vendors, this individual only recommends the spouse’s
company as the vendor. This is considered to be a(n):
a. accounting issue.
b. possible conflict of interest.
c. maintenance of confidentiality issue.
d. problem with resource allocation.
ANS: B
Concern has been raised over the interrelationships between practitioners in the
medical field and commercial suppliers of drugs, devices, equipment, etc., to
the medical profession.
Similarly, relationships have been scrutinized between clinical laboratorians and
manufacturers and providers of diagnostic equipment and supplies. These
concerns led the National Institutes of Health (NIH) in 1995 to require official
institutional review of financial disclosure by researchers and management of
situations in which disclosure indicates potential conflicts of interest.
DIF: 1 REF: Page 4-5 OBJ: 6 | 7
2. A patient visits her physician stating that her prescribed painkiller is not working
to reduce the pain following her recent surgery. A friend of the patient claims that
the same painkiller “worked wonders” to reduce her pain after the same surgery.
The physician states that the difference in the effect of the drug might be caused
by , which is studied in
pharmacogenetics.
a. epidemiology
b. an inherited disease
c. a conflict of interest
d. a genetic variation in drug-metabolizing enzymes
ANS: D
Pharmacogenetics is the study of the genetic variation of drug
metabolism between individuals.
DIF: 1 REF: Page 3 OBJ: 1
3. John works in a molecular diagnostics laboratory and receives a blood sample
that has the name of a close friend printed on the bar-coded label. The genetic
test that is ordered on the friend’s sample would provide diagnostic
information about a disorder that has a poor prognosis, and the test is usually
performed by John. He asks a fellow employee to analyze the sample for him
and not divulge the results. This ethical issue concerns:
a. confidentiality of patient genetic and medical information.
b. a conflict of interest.
lOMoAR cPSD| 22830792
TEST BANK FOR Tietz Fundamentals Ofclinical
ChemistryAND Molecular Diagnostics 7TH
Edition BY Burti
Psychiatric/Mental Health Nursing (Santa Fe College)
Smartprep Examinations
since 2010
[2010 1
, lOMoAR cPSD| 22830792
TEST BANK FOR TIETZ FUNDAMENTALS OFCLINICAL CHEMISTRY AND
MOLECULAR DIAGNOSTICS 7TH EDITION BYBURTIS
TABLE OF CONTENTS:
I. PRINCIPLES OF LABORATORY MEDICINE
1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
2. Selection and Analytical Evaluation of Methods — With Statistical
Techniques
3. Clinical Evaluation of Methods
4. Evidence-Based Laboratory Medicine
5. Establishment and Use of Reference Values
6. Specimen Collection, Processing, and Other Preanalytical Variables
7. Quality Management
II. ANALYTICAL TECHNIQUES AND INSTRUMENTATION
8. Principles of Basic Techniques and Laboratory Safety
9. Optical Techniques
10. Electrochemistry and Chemical Sensors
11. Electrophoresis
12.Chromatography
13.Mass Spectrometry
14.Enzyme and Rate Analyses
15.Immunochemical Techniques 16
Automation
17. Point-of-Care Instrumentation
III. ANALYTES
18. Amino Acids, Peptides, and Proteins
19. Serum Enzymes
20. Tumor Markers and Cancer Genes
21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
22. Carbohydrates
23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Fac- tors
24. Electrolytes and Blood Gases
25. Hormones
26. Catecholamines and Serotonin
27. Vitamins, Trace Elements, Nutritional Assessment
28. Hemoglobin, Iron, and Bilirubin
29. Porphyrins and Porphyrias
30. Therapeutic Drugs and Their Management
[2010 2
, lOMoAR cPSD| 22830792
31. Clinical Toxicology
32. Toxic Metals
IV. PATHOPHYSIOLOGY
33. Diabetes
34. Cardiovascular Disease
35. Kidney Disease
36. Physiology and Disorders of Water, Electrolyte, and Acid-Base
Metabolism
37. Liver Disease
38. Gastrointestinal and Pancreatic Diseases
39. Disorders of Bone and Mineral Metabolism
40. Disorders of the Pituitary Gland
41. Disorders of the Adrenal Cortex
42. Thyroid Disorders
43. Reproduction-Related Disorders
44. Pregnancy and Prenatal Testing
45. Newborn Screening and Inborn Errors of Metabolism
46. Pharmacogenetics
V. MOLECULAR DIAGNOSTICS NEW!
47. Principles of Molecular Biology
48. Nucleic Acid Techniques and Applications
49. Genomes and Nucleic Acid Alterations
VI. REFERENCE INFORMATION
50. Reference Information for the Clinical Laboratory
[2010 3
, lOMoAR cPSD| 22830792
Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory
Medicine Test Bank
MULTIPLE
CHOICE
1. An individual working in a clinical chemistry laboratory is married to a sales
representative who works for a company that sells chemistry laboratory
supplies. When the laboratory manager requests a list of needed supplies, cost
of supplies, and vendors, this individual only recommends the spouse’s
company as the vendor. This is considered to be a(n):
a. accounting issue.
b. possible conflict of interest.
c. maintenance of confidentiality issue.
d. problem with resource allocation.
ANS: B
Concern has been raised over the interrelationships between practitioners in the
medical field and commercial suppliers of drugs, devices, equipment, etc., to
the medical profession.
Similarly, relationships have been scrutinized between clinical laboratorians and
manufacturers and providers of diagnostic equipment and supplies. These
concerns led the National Institutes of Health (NIH) in 1995 to require official
institutional review of financial disclosure by researchers and management of
situations in which disclosure indicates potential conflicts of interest.
DIF: 1 REF: Page 4-5 OBJ: 6 | 7
2. A patient visits her physician stating that her prescribed painkiller is not working
to reduce the pain following her recent surgery. A friend of the patient claims that
the same painkiller “worked wonders” to reduce her pain after the same surgery.
The physician states that the difference in the effect of the drug might be caused
by , which is studied in
pharmacogenetics.
a. epidemiology
b. an inherited disease
c. a conflict of interest
d. a genetic variation in drug-metabolizing enzymes
ANS: D
Pharmacogenetics is the study of the genetic variation of drug
metabolism between individuals.
DIF: 1 REF: Page 3 OBJ: 1
3. John works in a molecular diagnostics laboratory and receives a blood sample
that has the name of a close friend printed on the bar-coded label. The genetic
test that is ordered on the friend’s sample would provide diagnostic
information about a disorder that has a poor prognosis, and the test is usually
performed by John. He asks a fellow employee to analyze the sample for him
and not divulge the results. This ethical issue concerns:
a. confidentiality of patient genetic and medical information.
b. a conflict of interest.
