BMW3010 – Multimorbiditeit in Obesitas – Case 2
WHAT KINDS OF MEASUREMENTS ARE USED TO ASSESS OBESITY ?
Reference Methods
o Whole-body 40K counting – used to estimate FM and FFM
Principle: based on measuring body cell mass
Disadvantage: relative high costs
o In vivo neutron activation analysis (IVNAA) – quantifies the main
elements in the atomic body composition level in vivo (H, C, N, O, P, Ca, Cl)
Principle: these elements can be used to calculate the components of
fat, protein, water and minerals.
Disadvantage: radiation exposure
o Hydrometry – estimates FM and FFM
Principle: quantifies body fluid compartments based on a labelled
tracer – a known dose of labelled water is administered to the subject
and the total body water (TBW) is calculated.
Assumption: homogenous division of labelled tracer
o Body volume-based body composition measurement – assumes that
the body has two main components (FM&FFM), with further partition of FFM
into TBW, protein, and minerals, all with known densities; percent fat is
calculated from body density (assumes stable densities of FM&FFM).
WHAT KINDS OF MEASUREMENTS ARE USED TO ASSESS OBESITY ?
Reference Methods
o Whole-body 40K counting – used to estimate FM and FFM
Principle: based on measuring body cell mass
Disadvantage: relative high costs
o In vivo neutron activation analysis (IVNAA) – quantifies the main
elements in the atomic body composition level in vivo (H, C, N, O, P, Ca, Cl)
Principle: these elements can be used to calculate the components of
fat, protein, water and minerals.
Disadvantage: radiation exposure
o Hydrometry – estimates FM and FFM
Principle: quantifies body fluid compartments based on a labelled
tracer – a known dose of labelled water is administered to the subject
and the total body water (TBW) is calculated.
Assumption: homogenous division of labelled tracer
o Body volume-based body composition measurement – assumes that
the body has two main components (FM&FFM), with further partition of FFM
into TBW, protein, and minerals, all with known densities; percent fat is
calculated from body density (assumes stable densities of FM&FFM).