PHARMACOLOGY MODULE EXAM 1

A patient recently started taking a new medication; he mentions to his doctor at his next appointment that he has noticed his mouth is extremely dry since starting the medication to the point where he is not able to eat. He has tried managing it with lozenges and increased liquids and nothing seems to work. What drug effect best describes the dry mouth this patient is experiencing? Side Effect Adverse Effect Toxic Effect Therapeutic Effect Discontinuing drug therapy is always the best course of action whenever a patient experiences a harmful adverse event. True False The site within the cell that a drug binds to in order to exert its therapeutic effect is known as the receptor. True False When a drug binds to a cell exerting its effect leading to a decrease in that cell’s physiologic response that drug is acting as an agonist. True False Matching 1.Duration of Action - Length of time the drug produces its effect 2.Onset of Action - Time from administration to first effect 3.Therapeutic Range - Drug concentration is above MEC and below MTC All drugs have both a trade name and a generic name True False There can be multiple generic names for the same chemical compound. True False Select the dosage form that is best described as a flattened tablet that dissolves in the mouth: Tablet Capsule Troche Suppository Tablets that are coated with an acid-resistant substance to prevent dissolution in the stomach are called delayed release. True False This study source was downloaded by from CourseH on :33:15 GMT -05:00 PHARMACOLOGY MODULE EXAM 1 Suppositories are designed to melt at body temperature. True False Parenteral administration generally has a slower onset of action than oral. True False Pharmacodynamics is the study of how various dosage forms influence the way in which drugs affect the body. True False Pharmacokinetics can also be thought of as what the drug does to the body. True False List the four components of the pharmacokinetic phase of drug activity. absorption, distribution, metabolism, excretion What term best describes the amount of drug that is absorbed into the body? Distribution Pharmaceutics Bioavailability Metabolism The primary factor that affects drug absorption is: Route of administration Timing Drug interactions Pharmacodynamics What is the name of the dosage form that makes drug acid resistant to prevent dissolution in the stomach? Enteric coating Examples of parenteral routes of administration include each of the following EXCEPT: Intravenous injection Inhalation Oral Topical Medications applied topically generally have an inconsistent and unreliable absorption into the bloodstream. True False Name the pharmacokinetic term that refers to the transport of drug by the bloodstream to the site of action. Distribution This study source was downloaded by from CourseH on :33:15 GMT -05:00 Give an example of an organ that would generally receive a drug first due to having a high blood supply. Heart, brain Name the part of the body that is the primary site of drug metabolism_____________. Liver Which of the following statements regarding drug metabolism is true. Drugs cannot act as a substrate of an enzyme within the liver. When a drug acts as an enzyme inhibitor this leads to more drug being metabolized. When a drug acts as an enzyme inducer this leads to more drug being metabolized. Liver enzymes are not a cause of many drug interactions. Name the primary organ responsible for the excretion of drugs from the body. Kidney How many half-lives does it take for most drugs to be effectively removed from the body? 3579 Drug A has a 24-hour half-life; drug B has a 3-hour half-life. Based on this information which drug would take longer to reach steady state? Drug A When thinking about pharmacodynamics, drugs can exert their action in each of the following ways except: Acting on receptors Targeting other drugs Acting on enzymes Targeting various cell processes A drug acting as an antagonist is best described as a drug that works by binding to a receptor and preventing the binding of other agonists. True False Drugs can interact with_________ most commonly inhibiting them from catalyzing reactions within cells. Enzymes Blood vessels Metabolites Receptors Generally as a patient ages they require more of a drug than their younger counterpart. True False Matching This study source was downloaded by from CourseH on :33:15 GMT -05:00