Molecular Genetics
, DNA is the Genetic Material
History
• Once chromosomes were known to carry
genes, the next question became- which of
the two organic compounds that make up
chromosomes (DNA or protein) was the
genetic material?
, Hershey and Chase
• Answered this question using bacteriophages
(viruses that infect bacteria)
• Radioactive phosphorous used to tag DNA
• Radioactive sulfur used to tag protein
• Results showed that only the DNA entered the
infected cell (the protein coat of the virus was
left outside the infected cell)
,