MICROBIOLOGY
,WHAT IS INDUSTRIAL
MICROBIOLOGY?
A branch of applied microbiology in which microorganisms are used for the
production of important substances by using techniques like Recombinant
DNA technology
1. Antibiotics,eg- Bacitracin(a cell wall synthesis inhibitor) produce from
bacteria Bacillus subtilis
2. Food products,eg- bread,vinegar,yoghurt and cheese
3. Enzymes,eg- proteases, amylases, cellulases, and lipases
4. Amino acids,eg- Amino Acid, L-Glutamic Acid, L-Lysine, L-Threonine, L-
Phenylalanine
Why We Use it ? To enhance the quality and yield of the products
(Ref-Kim et al., 2016; Zhang and Wang, 2016)
,INTRODUCTION TO
STERILIZATION
What is Sterilization?
A process that destroys or eliminates all forms of microbial life particularly
microorganisms such as fungi, bacteria, spores, and unicellular eukaryotic
organisms and other biological agents such as prions present in or on a
specific surface, object, or fluid.
1. parenteral administration
2. contact with broken skin
3. mucosal surfaces
4. sterilization of microbiological materials, soiled
dressings and other contaminated items is necessary to
minimize
, HOW WE ACHIEVE
STERILIZATION?
Following are the Processes that may be used for sterilization
1. High Temperature Eg- Moist heat(steam) sterilization and Dry heat
sterilization
2. Reactive gas/Gaseous Eg
3. Radiation Eg X-Rays and Gamma Rays
4. Physical sterilization Eg Filtration through a microorganism - proof filter.
5. Low Temperature Sterilization
6. Desiccation
7. Osmotic Pressure