1Chapter 01: Cellular Biology
Huether & McCance: Understanding Pathophysiology, 6th
Edition
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. It is observed to
have supercoiled DNA with histones. Which of the following would also
be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a
supercoiled DNA within its nucleus; thus, the nucleus should be
observed. A single circular chromosome called a prokaryote contains
free-floating nuclear material but has no organelles.
REF: p. 2
2. A nurse is instructing the staff about cellular functions. Which cellular
function is the nurse describing when an isolated cell absorbs oxygen
and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
The cell’s ability to absorb oxygen is referred to as respiration while its
communication ability involves maintenance of a steady dynamic
state, metabolic absorption provides nutrition, and secretion allows for
the synthesizing of new substances.
REF: p. 2
3. A eukaryotic cell is undergoing DNA replication. In which region of the
cell would most of the genetic information be contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm
ANS: C
, The region of the cell that contains genetic material, including a large
amount of ribonucleic acid, most of the DNA, and DNA-binding
proteins, is the nucleolus, which is located within the cell’s nucleus.
Mitochondria is associated with cellular respiration, while ribosomes
are involved with protein manufacturing. Cytoplasm is a fluid filling
that is a component of the cell.
REF: p. 2
4. Which of the following can remove proteins attached to the cell’s
bilayer by dissolving the layer itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
d. Cell adhesion molecules
ANS: B
Proteins directly attached to the membrane bilayer can be removed by
the action of integral membrane proteins that dissolve the bilayer.
Peripheral membrane proteins reside at the surface while cell adhesion
molecules are on the outside of the membrane. Glycoprotein marks
cells and does not float.
REF: p. 7
5. Which of the following can bind to plasma membrane receptors?
a. Oxygen
b. Ribosomes
c. Amphipathic lipids
d. Ligands
ANS: D
Ligands are the only specific molecules that can bind with receptors on
the cell membrane.
REF: p. 9
6. A nurse is reviewing a report from a patient with metastatic cancer.
What alternation in the extracellular matrix would support the
diagnosis of metastatic cancer?
a. Decreased fibronectin
b. Increased collagen
c. Decreased elastin
d. Increased glycoproteins
ANS: A
Only a reduced amount of fibronectin is found in some types of
Huether & McCance: Understanding Pathophysiology, 6th
Edition
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. It is observed to
have supercoiled DNA with histones. Which of the following would also
be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a
supercoiled DNA within its nucleus; thus, the nucleus should be
observed. A single circular chromosome called a prokaryote contains
free-floating nuclear material but has no organelles.
REF: p. 2
2. A nurse is instructing the staff about cellular functions. Which cellular
function is the nurse describing when an isolated cell absorbs oxygen
and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
The cell’s ability to absorb oxygen is referred to as respiration while its
communication ability involves maintenance of a steady dynamic
state, metabolic absorption provides nutrition, and secretion allows for
the synthesizing of new substances.
REF: p. 2
3. A eukaryotic cell is undergoing DNA replication. In which region of the
cell would most of the genetic information be contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm
ANS: C
, The region of the cell that contains genetic material, including a large
amount of ribonucleic acid, most of the DNA, and DNA-binding
proteins, is the nucleolus, which is located within the cell’s nucleus.
Mitochondria is associated with cellular respiration, while ribosomes
are involved with protein manufacturing. Cytoplasm is a fluid filling
that is a component of the cell.
REF: p. 2
4. Which of the following can remove proteins attached to the cell’s
bilayer by dissolving the layer itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
d. Cell adhesion molecules
ANS: B
Proteins directly attached to the membrane bilayer can be removed by
the action of integral membrane proteins that dissolve the bilayer.
Peripheral membrane proteins reside at the surface while cell adhesion
molecules are on the outside of the membrane. Glycoprotein marks
cells and does not float.
REF: p. 7
5. Which of the following can bind to plasma membrane receptors?
a. Oxygen
b. Ribosomes
c. Amphipathic lipids
d. Ligands
ANS: D
Ligands are the only specific molecules that can bind with receptors on
the cell membrane.
REF: p. 9
6. A nurse is reviewing a report from a patient with metastatic cancer.
What alternation in the extracellular matrix would support the
diagnosis of metastatic cancer?
a. Decreased fibronectin
b. Increased collagen
c. Decreased elastin
d. Increased glycoproteins
ANS: A
Only a reduced amount of fibronectin is found in some types of
