NURS PHARMACOLOGY EXAM CH 11: Corticosteroids in
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
MULTIPLE CHOICE
1. A significant side effect of corticosteroid use is inhibition
of
a. IgE.
b. PDE.
c. HPA axis.
d. SRS-A.
ANS: C
When the body produces endogenous glucocorticoids, there is a normal feedback mechanism within the
hypothalamic-pituitary–adrenal (HPA) axis to limit production. As glucocorticoid levels increase, the
release of corticotropin-releasing factor (CRF) and adrenocorticotropic hormone (ACTH) is inhibited, and
further adrenal production is stopped. Because the body cannot distinguish between its own endogenous
glucocorticoids and exogenous glucocorticoid drugs, steroid administration can inhibit the hypothalamus
and pituitary glands, decreasing adrenal production. Immunoglobulin E (IgE), phosphodiesterase (PDE),
and slow-reacting substance of anaphylaxis (SRS-A) are not involved in this process.
REF: p. 184
2. Which of the following is produced in the hypothalamus?
a.
Glucocorticoids
b.
Corticotropin-releasing factor
,NURS PHARMACOLOGY EXAM CH 11: Corticosteroids in
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
c.
Mineralocorticoids
d.
Sex hormones
ANS: B
Three types of corticosteroid hormones are produced by the adrenal cortex: glucocorticoids,
mineralocorticoids, and sex hormones. Corticotropin-releasing factor (CRF) is released from the
hypothalamus.
REF: p. 184
3. Corticosteroids normally produced by the body are known as
a.
endogenous.
b.
exogenous.
c.
extrinsic.
d.
intrinsic.
ANS: A
Endogenous corticosteroids are produced inside the human body, whereas exogenous corticosteroids are
produced outside the body.
REF: p. 184
4. Which of the following are examples of steroids or steroid combinations available
for inhalation?
1. AeroSpan
2. Flovent
3. Qvar
,NURS PHARMACOLOGY EXAM CH 11: Corticosteroids in
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
4. Advair
a.
1, 2, and 3 only
b.
1 and 2 only
c.
2 and 3 only
d. 1, 2, 3, and 4
ANS: D
Brand names of corticosteroids available by aerosol for oral inhalation include Qvar, AeroSpan,
Asmanex, Flovent, Pulmicort, and Advair. Interleukins are cytokines released by the human
body.
REF: p. 185
5. The rise and fall of levels of glucocorticoids in the body follow what kind of rhythm?
a. Weekly
b. Monthly
c. Circadian
d. No set rhythm
ANS: C
The production of the body’s own glucocorticoids follows a rhythmic cycle, termed a diurnal or
circadian
rhythm.
REF: p. 187
, NURS PHARMACOLOGY EXAM CH 11: Corticosteroids in
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
6. The inflammatory process includes which of the following activities?
1. Mediator cascade
2. Increased vascular permeability
3. Leukocytic infiltration
4. Phagocytosis
a.
1 and 2 only
b.
2 and 3 only
c.
1, 2, and 4 only
d. 1, 2, 3, and 4
ANS: D
The process of inflammation is caused by the following four major categories of activity:
1. Mediator cascade
2. Increased vascular permeability
3. Leukocytic infiltration
4. Phagocytosis
REF: p. 188
7. The major cells responsible for an inflammatory response in asthma are
a.
macrophages and mast cells.
b.
mast cells and eosinophils.
c.
T lymphocytes and macrophages.
d.
basophils and SRS-A.
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
MULTIPLE CHOICE
1. A significant side effect of corticosteroid use is inhibition
of
a. IgE.
b. PDE.
c. HPA axis.
d. SRS-A.
ANS: C
When the body produces endogenous glucocorticoids, there is a normal feedback mechanism within the
hypothalamic-pituitary–adrenal (HPA) axis to limit production. As glucocorticoid levels increase, the
release of corticotropin-releasing factor (CRF) and adrenocorticotropic hormone (ACTH) is inhibited, and
further adrenal production is stopped. Because the body cannot distinguish between its own endogenous
glucocorticoids and exogenous glucocorticoid drugs, steroid administration can inhibit the hypothalamus
and pituitary glands, decreasing adrenal production. Immunoglobulin E (IgE), phosphodiesterase (PDE),
and slow-reacting substance of anaphylaxis (SRS-A) are not involved in this process.
REF: p. 184
2. Which of the following is produced in the hypothalamus?
a.
Glucocorticoids
b.
Corticotropin-releasing factor
,NURS PHARMACOLOGY EXAM CH 11: Corticosteroids in
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
c.
Mineralocorticoids
d.
Sex hormones
ANS: B
Three types of corticosteroid hormones are produced by the adrenal cortex: glucocorticoids,
mineralocorticoids, and sex hormones. Corticotropin-releasing factor (CRF) is released from the
hypothalamus.
REF: p. 184
3. Corticosteroids normally produced by the body are known as
a.
endogenous.
b.
exogenous.
c.
extrinsic.
d.
intrinsic.
ANS: A
Endogenous corticosteroids are produced inside the human body, whereas exogenous corticosteroids are
produced outside the body.
REF: p. 184
4. Which of the following are examples of steroids or steroid combinations available
for inhalation?
1. AeroSpan
2. Flovent
3. Qvar
,NURS PHARMACOLOGY EXAM CH 11: Corticosteroids in
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
4. Advair
a.
1, 2, and 3 only
b.
1 and 2 only
c.
2 and 3 only
d. 1, 2, 3, and 4
ANS: D
Brand names of corticosteroids available by aerosol for oral inhalation include Qvar, AeroSpan,
Asmanex, Flovent, Pulmicort, and Advair. Interleukins are cytokines released by the human
body.
REF: p. 185
5. The rise and fall of levels of glucocorticoids in the body follow what kind of rhythm?
a. Weekly
b. Monthly
c. Circadian
d. No set rhythm
ANS: C
The production of the body’s own glucocorticoids follows a rhythmic cycle, termed a diurnal or
circadian
rhythm.
REF: p. 187
, NURS PHARMACOLOGY EXAM CH 11: Corticosteroids in
Respiratory Care QUESTIONS WITH CORRECT
ANSWERS 2023 A+ RATED
6. The inflammatory process includes which of the following activities?
1. Mediator cascade
2. Increased vascular permeability
3. Leukocytic infiltration
4. Phagocytosis
a.
1 and 2 only
b.
2 and 3 only
c.
1, 2, and 4 only
d. 1, 2, 3, and 4
ANS: D
The process of inflammation is caused by the following four major categories of activity:
1. Mediator cascade
2. Increased vascular permeability
3. Leukocytic infiltration
4. Phagocytosis
REF: p. 188
7. The major cells responsible for an inflammatory response in asthma are
a.
macrophages and mast cells.
b.
mast cells and eosinophils.
c.
T lymphocytes and macrophages.
d.
basophils and SRS-A.
