AVIAN MYCOPLASMOSIS
Poultry Pathology (Path-611)
Lecture 23-24
Dr. Muhammad Kashif Saleemi
DVM, M.Sc (Hons.), PhD
Associate Professor (Tenured)
Member National Disease Control Committee (NDCC)
US-NAS One Health Fellowship
Head Diagnostic Laboratory Department of Pathology
Department of Pathology, Faculty of Veterinary Science,
University of Agriculture, Faisalabad, Pakistan
, Definition and Occurrence
◼ Mycoplasmas belong to the Order Mycoplasmatales, are
the smallest prokaryotic organism (DNA content)
cultivatable on artificial medium and are completely devoid
of a cell wall.
◼ The absence of a cell wall accounts for their pleomorphic
shape, fried-egg colony appearance and their resistance
to penicillin-like antibiotics
◼ More than 20 species have identified, Four mycoplasma
species are considered pathogenic to commercial poultry
◼ Mycoplasma gallisepticum, M. synoviae, M. meleagridis
and M. iowae.
◼ Pathogenic species generally infect the respiratory system
but other systems may also be involved.
, Definition and Occurrence
◼ The cultivation of Mycoplasma sp. is somewhat difficult
and requires specialized media containing 10–15% serum,
yeast-derived components and unique factors for certain
species.
◼ Colony morphology is variable but it is characterized by a
“fried-egg” appearance.
◼ Identification to the species level is usually based on
immunologic tests utilizing species-specific antisera or
amplified DNA type tests
◼ Inoculation of 5-7 day-old embryos is an alternative
isolation procedure utilized (artificial media is unrewarding)
, ◼ MYCOPLASMA GALLISEPTICUM
INFECTION
◼ (MG; Chronic Respiratory Disease;
CRD; Infectious Sinusitis of Turkeys
Poultry Pathology (Path-611)
Lecture 23-24
Dr. Muhammad Kashif Saleemi
DVM, M.Sc (Hons.), PhD
Associate Professor (Tenured)
Member National Disease Control Committee (NDCC)
US-NAS One Health Fellowship
Head Diagnostic Laboratory Department of Pathology
Department of Pathology, Faculty of Veterinary Science,
University of Agriculture, Faisalabad, Pakistan
, Definition and Occurrence
◼ Mycoplasmas belong to the Order Mycoplasmatales, are
the smallest prokaryotic organism (DNA content)
cultivatable on artificial medium and are completely devoid
of a cell wall.
◼ The absence of a cell wall accounts for their pleomorphic
shape, fried-egg colony appearance and their resistance
to penicillin-like antibiotics
◼ More than 20 species have identified, Four mycoplasma
species are considered pathogenic to commercial poultry
◼ Mycoplasma gallisepticum, M. synoviae, M. meleagridis
and M. iowae.
◼ Pathogenic species generally infect the respiratory system
but other systems may also be involved.
, Definition and Occurrence
◼ The cultivation of Mycoplasma sp. is somewhat difficult
and requires specialized media containing 10–15% serum,
yeast-derived components and unique factors for certain
species.
◼ Colony morphology is variable but it is characterized by a
“fried-egg” appearance.
◼ Identification to the species level is usually based on
immunologic tests utilizing species-specific antisera or
amplified DNA type tests
◼ Inoculation of 5-7 day-old embryos is an alternative
isolation procedure utilized (artificial media is unrewarding)
, ◼ MYCOPLASMA GALLISEPTICUM
INFECTION
◼ (MG; Chronic Respiratory Disease;
CRD; Infectious Sinusitis of Turkeys
