Neoplastic Diseases of Chicken
Leukosis: Sarcoma Group
Poultry Pathology(Path-611)
Dr. Muhammad Kashif Saleemi
DVM PhD
Associate Professor (Tenured)
Member NDCC
Department of Pathology, Faculty of Veterinary Science,
University of Agriculture, Faisalabad, Pakistan
, Introduction and History
◼ The leukosis /sarcoma (L/S) group of diseases designates a
variety of benign and malignant neoplasms of chickens caused
by members of family Retroviridae
◼ Members of this group are characterized by possession of an
enzyme reverse transcriptase, which directs the synthesis of the
proviral DNA form of the RNA virus that forms part of the retroviral
life cycle and from which the family name is derived.
◼ Lymphoid leukosis (LL) has been the most common form of L/S
group of diseases seen in field flocks, although myeloid leukosis
also has become prevalent.
◼ The first report of LL is attributed to Roloff in 1868. However, the
disease was not well characterized until a basis for its separation
from MD was established in 1962.
,
Leukosis: Sarcoma Group
Poultry Pathology(Path-611)
Dr. Muhammad Kashif Saleemi
DVM PhD
Associate Professor (Tenured)
Member NDCC
Department of Pathology, Faculty of Veterinary Science,
University of Agriculture, Faisalabad, Pakistan
, Introduction and History
◼ The leukosis /sarcoma (L/S) group of diseases designates a
variety of benign and malignant neoplasms of chickens caused
by members of family Retroviridae
◼ Members of this group are characterized by possession of an
enzyme reverse transcriptase, which directs the synthesis of the
proviral DNA form of the RNA virus that forms part of the retroviral
life cycle and from which the family name is derived.
◼ Lymphoid leukosis (LL) has been the most common form of L/S
group of diseases seen in field flocks, although myeloid leukosis
also has become prevalent.
◼ The first report of LL is attributed to Roloff in 1868. However, the
disease was not well characterized until a basis for its separation
from MD was established in 1962.
,
