1.A patient has had endured several dosage adjustments of his tricyclic antidepressant, so the provider
recommends genetic testing. Which statement correctly describes the rationale for genetic testing?
(1/1 Point)
The CYP2D6 gene influences metabolism of tricyclic antidepressants and certain other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene that codes for color
blindness in men. Metabolism of 25% of all prescribed drugs, including tricyclic antidepressants, beta
adrenergic receptor blockers, and neuroleptics, is influenced by variants in a certain gene, requiring
genetic testing to reduce trial-and-error in estimating appropriate drug-dosage levels.
The HER2 gene is a tumor marker that impacts metabolism of tricyclic antidepressants.
The BRCA2 gene influences metabolism of certain drugs and increases the risk for breast cancer.
The x linked OPN1MW gene for male color blindness also slows metabolism of certain
2.According to the Centers for Disease Control and Prevention, the 10 most costly chronic conditions
include cardiovascular diseases, obesity, asthma, diabetes, smoking and alcohol related conditions,
cancer, Alzheimer's disease, arthritis and stroke. Which are the top 4 in ranking from most costly to least
costly?
(0/1 Point)
Cardiovascular diseases, obesity, diabetes, cancer
Cardiovascular diseases, diabetes, obesity, cancer
Cardiovascular diseases, Smoking-related conditions, Alcohol-related conditions, diabetes
Cardiovascular diseases, Stroke, Obesity, Diabetes
3.A mother brought her child to the doctor for genetic testing. The health care provider was trying to
explain the genetic results of the child. During his explanation he tell the mother that the child has 2 X
chromosomes and a Y chromosome in each cell. He begins to explain some physical appears the mother
might notice on her son. He explains that she might notice that he has sparse body hair, long limbs and
small testes. The health care practitioner is explaining which syndrome to the mother.
(1/1 Point)
Klinefelter syndrome
Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y chromosome in each cell.
Because of the Y chromosome these individuals have a male appearance, but they are usually sterile and
about half develop female-like breasts.
Turners’ syndrome
Down syndrome
, Kawasaki’s disease
4.A patient reports a maternal family history of Lynch syndrome. Which laboratory finding might indicate
a need for further testing for the presence of Lynch syndrome in this patient?
(1/1 Point)
Elevated thyroid-stimulating hormone
Low cortisol level
Positive heme-occult test
Positive heme-occult because Lynch syndrome is a hereditary form of colorectal cancer and colorectal
bleeding can be a sign of cancer
Sputum positive for Pseudomonas Aeruginosa
5.5. An individual’s acquired immunity is dependent on the function of which cells? (Select all that
apply.)
(0/1 Point)
Neutrophils
B lymphocytes
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in acquired immunity.
Opsonins
T lymphocytes
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in acquired immunity.
Macrophages
6.A 17-year-old female comes to the clinic for a physical exam. As part of the visit, the APRN considers
her risk factors for type 2 diabetes mellitus (T2DM). Risk factors for T2DM would likely include all of the
following except:
(0/1 Point)
Obesity
Native American ancestry
Family history of type 1 diabetes mellitus (T1DM)
Personal history of polycystic ovary syndrome (PCOS)
recommends genetic testing. Which statement correctly describes the rationale for genetic testing?
(1/1 Point)
The CYP2D6 gene influences metabolism of tricyclic antidepressants and certain other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene that codes for color
blindness in men. Metabolism of 25% of all prescribed drugs, including tricyclic antidepressants, beta
adrenergic receptor blockers, and neuroleptics, is influenced by variants in a certain gene, requiring
genetic testing to reduce trial-and-error in estimating appropriate drug-dosage levels.
The HER2 gene is a tumor marker that impacts metabolism of tricyclic antidepressants.
The BRCA2 gene influences metabolism of certain drugs and increases the risk for breast cancer.
The x linked OPN1MW gene for male color blindness also slows metabolism of certain
2.According to the Centers for Disease Control and Prevention, the 10 most costly chronic conditions
include cardiovascular diseases, obesity, asthma, diabetes, smoking and alcohol related conditions,
cancer, Alzheimer's disease, arthritis and stroke. Which are the top 4 in ranking from most costly to least
costly?
(0/1 Point)
Cardiovascular diseases, obesity, diabetes, cancer
Cardiovascular diseases, diabetes, obesity, cancer
Cardiovascular diseases, Smoking-related conditions, Alcohol-related conditions, diabetes
Cardiovascular diseases, Stroke, Obesity, Diabetes
3.A mother brought her child to the doctor for genetic testing. The health care provider was trying to
explain the genetic results of the child. During his explanation he tell the mother that the child has 2 X
chromosomes and a Y chromosome in each cell. He begins to explain some physical appears the mother
might notice on her son. He explains that she might notice that he has sparse body hair, long limbs and
small testes. The health care practitioner is explaining which syndrome to the mother.
(1/1 Point)
Klinefelter syndrome
Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y chromosome in each cell.
Because of the Y chromosome these individuals have a male appearance, but they are usually sterile and
about half develop female-like breasts.
Turners’ syndrome
Down syndrome
, Kawasaki’s disease
4.A patient reports a maternal family history of Lynch syndrome. Which laboratory finding might indicate
a need for further testing for the presence of Lynch syndrome in this patient?
(1/1 Point)
Elevated thyroid-stimulating hormone
Low cortisol level
Positive heme-occult test
Positive heme-occult because Lynch syndrome is a hereditary form of colorectal cancer and colorectal
bleeding can be a sign of cancer
Sputum positive for Pseudomonas Aeruginosa
5.5. An individual’s acquired immunity is dependent on the function of which cells? (Select all that
apply.)
(0/1 Point)
Neutrophils
B lymphocytes
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in acquired immunity.
Opsonins
T lymphocytes
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in acquired immunity.
Macrophages
6.A 17-year-old female comes to the clinic for a physical exam. As part of the visit, the APRN considers
her risk factors for type 2 diabetes mellitus (T2DM). Risk factors for T2DM would likely include all of the
following except:
(0/1 Point)
Obesity
Native American ancestry
Family history of type 1 diabetes mellitus (T1DM)
Personal history of polycystic ovary syndrome (PCOS)
