, a. Cause-specific mortality rate.64.65
=(Total number of deaths due to x cause / total population at mid year) x 1,000
=(No.of deaths from leukemia in one year in children younger than 10 years of age /
No.of children in the population younger than 10 years of age at midyear) x 1,000
b. Annual mortality rate .64
-annual death rate, or mortality rate from all causes.
(total # of deaths from all causes in 1 year / total population at mid year ) x 1,000
c. Case-fatality.65
--what percentage of people who have a certain disease die within a certain time after
their disease was diagnosed?
=(# of deaths due to a certain disease/total # suffering from that disease) x 100 %
-Measure of the severity of the disease
-As therapy improves, case-fatality would be expected to decline.
d. Proportionate mortality.This is Not a rate. 66
-the proportionate mortality from cardiovascular disease in the U.S. in 2010 (percent, %)
-of all deaths in the US, what proportion was caused by cardiovascular disease?
=( # of deaths from cardiovascular diseases in US in 2010 / total deaths in the US in 2010)
x 100
5. Assess the Validity.89 and Reliability105.110 of Diagnostic and Screening Tests
a. Define, compare and calculate measures of validity, including sensitivity and specificity.
-Validity of test: its ability to distinguish between who has a disease and who does not.
-Sensitivity of test is defined as the ability of the test to identify correctly those who have
the disease.
-Specificity of test is defined as the ability of the test to identify correctly those who do
not have the disease.
Have a Disease Do not have Disease
Positive True Positive (TP) False Positive (FP) Positive
Have the disease Do not have the predictive value
And test positive disease =
But test positive (TP/TP+FP)x100
a b =(a/a+b)x100
Negative False Negative (FN) True Negative (TN) Negative