Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition)
MULTIPLE CHOICE
1. What congenital malformation is commonly linked to acute leukemia in children?
a. Down syndrome
, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition)
b. Wilms tumor
c. Retinoblastoma
d. Neuroblastoma
ANS: A
Trisomy 21 (Down syndrome) is the most common genetic defect linked to the development of acute
leukemia. Children with Down syndrome have a 10- to 20-fold increased risk of developing acute
lymphoblastic and myelogenous leukemia and a higher risk for developing acute megakaryocytic
leukemia. No current research supports a link between Wilms tumor, retinoblastoma, or
neuroblastoma and acute leukemia.
PTS: 1 DIF: Cognitive Level: Remembering
2. When are childhood cancers most often diagnosed?
a. During infancy
b. At peak times of physical growth
c. After diagnosis of a chronic illness
d. After an acute illness
ANS: B
Childhood cancers are most often diagnosed during peak times of physical growth. No current
research supports the association between frequency of diagnosis and infancy, chronic illness, or
acute illness.
PTS: 1 DIF: Cognitive Level: Remembering
3. Prenatal exposure to diethylstilbestrol (DES) can result in which type of cancer?
a. Breast cancer
b. Leukemia
c. Vaginal cancer
d. Lymphoma
ANS: C
DES has been identified as a transplacental chemical carcinogen; a small percentage of the daughters
of women who took DES during pregnancy developed adenocarcinomas of the vagina. No current
research supports a link between the drug and other cancers.
PTS: 1 DIF: Cognitive Level: Remembering
4. Currently, what percentage of children with cancer can be cured?
a. 40%
b. 50%
c. 60%
d. 85%
ANS: D
Currently, more than 85% of children diagnosed with cancer are cured.
PTS: 1 DIF: Cognitive Level: Remembering
MULTIPLE CHOICE
1. What congenital malformation is commonly linked to acute leukemia in children?
a. Down syndrome
, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition)
b. Wilms tumor
c. Retinoblastoma
d. Neuroblastoma
ANS: A
Trisomy 21 (Down syndrome) is the most common genetic defect linked to the development of acute
leukemia. Children with Down syndrome have a 10- to 20-fold increased risk of developing acute
lymphoblastic and myelogenous leukemia and a higher risk for developing acute megakaryocytic
leukemia. No current research supports a link between Wilms tumor, retinoblastoma, or
neuroblastoma and acute leukemia.
PTS: 1 DIF: Cognitive Level: Remembering
2. When are childhood cancers most often diagnosed?
a. During infancy
b. At peak times of physical growth
c. After diagnosis of a chronic illness
d. After an acute illness
ANS: B
Childhood cancers are most often diagnosed during peak times of physical growth. No current
research supports the association between frequency of diagnosis and infancy, chronic illness, or
acute illness.
PTS: 1 DIF: Cognitive Level: Remembering
3. Prenatal exposure to diethylstilbestrol (DES) can result in which type of cancer?
a. Breast cancer
b. Leukemia
c. Vaginal cancer
d. Lymphoma
ANS: C
DES has been identified as a transplacental chemical carcinogen; a small percentage of the daughters
of women who took DES during pregnancy developed adenocarcinomas of the vagina. No current
research supports a link between the drug and other cancers.
PTS: 1 DIF: Cognitive Level: Remembering
4. Currently, what percentage of children with cancer can be cured?
a. 40%
b. 50%
c. 60%
d. 85%
ANS: D
Currently, more than 85% of children diagnosed with cancer are cured.
PTS: 1 DIF: Cognitive Level: Remembering
