#1 is C.
Week 1 Quiz
• What does volume neurotransmission refer to?
The diffusion of neurotransmitter to nearby neurons.
• What does retrograde neurotransmissions refer to?
The flow of neurotransmitter from postsynaptic neuron to
presynaptic neuron
• Using the following CYP450 table to hypothesize drug
interactions and their clinical significance for a patient
on clozapine who carbamazepine, a mood stabilizer?
Clozapine levels would decrease, placing the patient at
risk for re-emergence of psychotic symptoms.
• Elimination of a drug can be impacted by all of the
following scenarios except? A Mediterranean diet.
• Which of the following statements is true about ligand-
gated ion channels? Allosteric modulators can enhance
or inhibit ion channels when in the presence of
neurotransmitter.
• Pharmacokinetics involves consideration all of the following
except the?
Receptor binding site of the drug
• The direct role of
transcription factors is to?
Influence gene expression
,• Second messengers are?
Intracellular messengers activated by extracellular
messengers.
• Which of the following statements about pharmacokinetics is
true?
Accumulation of psychotropic drugs occurs faster in the brain
then adipose tissue.
• G-linked proteins?
Bind enzymes that synthesize second messengers.
• Carbamazepine has a half-life of approximately 12 hours.
The clinical implications of this are?
Therapeutic blood monitoring of carbamazepine should not
occur before 2 ½ days of starting the medication.
• When an inverse agonist binds to a G-protein linked receptor,
signal transduction is?
Inactivated.
• When an antagonist binds to a G-protein-linked receptor,
signal transduction is?
Unchanged.
• Which of the following statements is true about
concentration-time curve of medication absorption?
Steady-state refers to the point at which blood level
fluctuations are mild and not clinically significant.
• When an agonist binds to a G-protein-linked receptor, signal
transduction is?
Fully enhanced.
• The two main targets of signal
transduction cascades are? Gene
expression and phosphoproteins.
• Which of the following methods of drug delivery is slowest to
reach the bloodstreams?
Oral pills.
• When a partial agonist binds to a G-protein-linked receptor,
signal transduction is?
Partially enhanced.
, • When comparing phase I and phase II metabolism which of
the following statements is true?
Phase I metabolism refers to CYP450 enzyme activity whereas
Phase II metabolism refers to conjugation of drug.
• Enzyme inhibition as a target of drug therapies is?
A means of preventing the degradation of neurotransmitters.
• In ligand-gated ion channels, an?
Antagonist, in the presence of an agonist, can return a
channel to resting state.
• Which of the following statements about drug
absorption is trued? Concurrent use of some
medications can slow absorption.
• A neurotransmitter binds to a receptor, causing electrical
impulses to travel the neurons axon; it eventually releases
the neurotransmitter and repeats the process with a
postsynaptic neuron. Which type of neurotransmission does
this describe?
Classic synaptic neurotransmission
• Which of the following statements is true about drug
distribution?
Protein binding of psychotropic drugs can impact their
availability at receptor sites.
• Which of the following statements is true about
neuronal gene expression? Environmental factors
can alter a neurons gene expression.
• First pass effect refers to the?
Metabolism of the drug in the liver, prior to reaching systemic
circulation
• Matching the following.
Pharmacodynamics- Action of
drugs on the body
Pharmacokinetics- Action of the
body on the drugs
Axon- The fiber-like part of the neuron that sends
Week 1 Quiz
• What does volume neurotransmission refer to?
The diffusion of neurotransmitter to nearby neurons.
• What does retrograde neurotransmissions refer to?
The flow of neurotransmitter from postsynaptic neuron to
presynaptic neuron
• Using the following CYP450 table to hypothesize drug
interactions and their clinical significance for a patient
on clozapine who carbamazepine, a mood stabilizer?
Clozapine levels would decrease, placing the patient at
risk for re-emergence of psychotic symptoms.
• Elimination of a drug can be impacted by all of the
following scenarios except? A Mediterranean diet.
• Which of the following statements is true about ligand-
gated ion channels? Allosteric modulators can enhance
or inhibit ion channels when in the presence of
neurotransmitter.
• Pharmacokinetics involves consideration all of the following
except the?
Receptor binding site of the drug
• The direct role of
transcription factors is to?
Influence gene expression
,• Second messengers are?
Intracellular messengers activated by extracellular
messengers.
• Which of the following statements about pharmacokinetics is
true?
Accumulation of psychotropic drugs occurs faster in the brain
then adipose tissue.
• G-linked proteins?
Bind enzymes that synthesize second messengers.
• Carbamazepine has a half-life of approximately 12 hours.
The clinical implications of this are?
Therapeutic blood monitoring of carbamazepine should not
occur before 2 ½ days of starting the medication.
• When an inverse agonist binds to a G-protein linked receptor,
signal transduction is?
Inactivated.
• When an antagonist binds to a G-protein-linked receptor,
signal transduction is?
Unchanged.
• Which of the following statements is true about
concentration-time curve of medication absorption?
Steady-state refers to the point at which blood level
fluctuations are mild and not clinically significant.
• When an agonist binds to a G-protein-linked receptor, signal
transduction is?
Fully enhanced.
• The two main targets of signal
transduction cascades are? Gene
expression and phosphoproteins.
• Which of the following methods of drug delivery is slowest to
reach the bloodstreams?
Oral pills.
• When a partial agonist binds to a G-protein-linked receptor,
signal transduction is?
Partially enhanced.
, • When comparing phase I and phase II metabolism which of
the following statements is true?
Phase I metabolism refers to CYP450 enzyme activity whereas
Phase II metabolism refers to conjugation of drug.
• Enzyme inhibition as a target of drug therapies is?
A means of preventing the degradation of neurotransmitters.
• In ligand-gated ion channels, an?
Antagonist, in the presence of an agonist, can return a
channel to resting state.
• Which of the following statements about drug
absorption is trued? Concurrent use of some
medications can slow absorption.
• A neurotransmitter binds to a receptor, causing electrical
impulses to travel the neurons axon; it eventually releases
the neurotransmitter and repeats the process with a
postsynaptic neuron. Which type of neurotransmission does
this describe?
Classic synaptic neurotransmission
• Which of the following statements is true about drug
distribution?
Protein binding of psychotropic drugs can impact their
availability at receptor sites.
• Which of the following statements is true about
neuronal gene expression? Environmental factors
can alter a neurons gene expression.
• First pass effect refers to the?
Metabolism of the drug in the liver, prior to reaching systemic
circulation
• Matching the following.
Pharmacodynamics- Action of
drugs on the body
Pharmacokinetics- Action of the
body on the drugs
Axon- The fiber-like part of the neuron that sends
