Pharmacology Assignment 1: Case Study
Norquest College
PHAR 1000 A01
Patrick Kelly
Assignment 1: Case Study
May 25, 2021
, Captopril (Generic), Trade name of Capoten was discontinued according
Medication to Davis Drug Guide (2021).
Levothyroxine (Generic), Eltroxin (Trade)
Medication Diagnosis
- Captopril: Hypertension related to coronary artery disease
- Levothyroxine: Thyroid supplementation in hypothyroidism
Mechanism of Action (effect)
- Captopril: “ACE inhibitors block the conversion of angiotensin I
to the vasoconstrictor angiotensin II.” (Vallerand & Sanoski, 2021,
Right Medication p. 161)
& Right Reason - Levothyroxine: “Synthetic form of thyroxine (T4). Replacement
of or supplements to endogenous thyroid hormones.” (Vallerand &
Sanoski, 2021, p. 161)
Pharmacological Class
- Captopril: “ACE inhibitor” (Lilley, et al., 2019, pg. 382)
- Levothyroxine: “Synthetic levothyroxine (thyroid hormone T4)”
(Lilley, et al., 2019, pg. 531)
Captopril: Yes, the dose ordered by the doctor is a safe dosage. The
doctor's order is 25 mg PO two times daily after meals. A recommended
dose for adults with hypertension PO is 12.5 - 25 mg 2-3 times daily as
per the Davis Drug Guide 17th edition, page 163, (2021). A total amount
of Captopril administered in 24 hours is 50 mg.
Levothyroxine: Yes, the dose ordered by the doctor is a safe dosage. The
doctor’s order is 75 mcg PO in the morning (AM) before meals. A
recommended dose for an adult is“50 mcg as a single dose initially, a
Right Dose
usual maintenance dose is 75-125mcg/day (1.5mcg/kg/day)” as per the
Davis Drug Guide 17th edition, page 782, (2021). A total amount of
Levothyroxine in 24 hours is 75 mcg.
Drug calculation:
• Captopril: 25mg/12.5mg x1 tab = 2 tabs Tablets PO BID after
meals
• Levothyroxine: 75mcg/50mcg x 1 tab = 1.5 Tablets PO in AM
before meals
Captopril: The time this drug is ordered to be taken is 2 times daily
before meals, which is correct for this drug. Captopril can be given “12.5-
50 mg 2-3 times daily with a maximum dose of 450 mg/day” (Vallerand
Right Time & Sanoski, 2021, p. 163).
Levothyroxine: The time this drug is ordered to be taken is once daily
before morning meals, which is correct for this drug. Levothyroxine can
be given “75-125 mcg/day” (Vallerand & Sanoski, 2021, p. 163).
Right Route Captopril: Administered by the right route. Captopril can come in oral
Norquest College
PHAR 1000 A01
Patrick Kelly
Assignment 1: Case Study
May 25, 2021
, Captopril (Generic), Trade name of Capoten was discontinued according
Medication to Davis Drug Guide (2021).
Levothyroxine (Generic), Eltroxin (Trade)
Medication Diagnosis
- Captopril: Hypertension related to coronary artery disease
- Levothyroxine: Thyroid supplementation in hypothyroidism
Mechanism of Action (effect)
- Captopril: “ACE inhibitors block the conversion of angiotensin I
to the vasoconstrictor angiotensin II.” (Vallerand & Sanoski, 2021,
Right Medication p. 161)
& Right Reason - Levothyroxine: “Synthetic form of thyroxine (T4). Replacement
of or supplements to endogenous thyroid hormones.” (Vallerand &
Sanoski, 2021, p. 161)
Pharmacological Class
- Captopril: “ACE inhibitor” (Lilley, et al., 2019, pg. 382)
- Levothyroxine: “Synthetic levothyroxine (thyroid hormone T4)”
(Lilley, et al., 2019, pg. 531)
Captopril: Yes, the dose ordered by the doctor is a safe dosage. The
doctor's order is 25 mg PO two times daily after meals. A recommended
dose for adults with hypertension PO is 12.5 - 25 mg 2-3 times daily as
per the Davis Drug Guide 17th edition, page 163, (2021). A total amount
of Captopril administered in 24 hours is 50 mg.
Levothyroxine: Yes, the dose ordered by the doctor is a safe dosage. The
doctor’s order is 75 mcg PO in the morning (AM) before meals. A
recommended dose for an adult is“50 mcg as a single dose initially, a
Right Dose
usual maintenance dose is 75-125mcg/day (1.5mcg/kg/day)” as per the
Davis Drug Guide 17th edition, page 782, (2021). A total amount of
Levothyroxine in 24 hours is 75 mcg.
Drug calculation:
• Captopril: 25mg/12.5mg x1 tab = 2 tabs Tablets PO BID after
meals
• Levothyroxine: 75mcg/50mcg x 1 tab = 1.5 Tablets PO in AM
before meals
Captopril: The time this drug is ordered to be taken is 2 times daily
before meals, which is correct for this drug. Captopril can be given “12.5-
50 mg 2-3 times daily with a maximum dose of 450 mg/day” (Vallerand
Right Time & Sanoski, 2021, p. 163).
Levothyroxine: The time this drug is ordered to be taken is once daily
before morning meals, which is correct for this drug. Levothyroxine can
be given “75-125 mcg/day” (Vallerand & Sanoski, 2021, p. 163).
Right Route Captopril: Administered by the right route. Captopril can come in oral
